Grant W Montgomery

No ORCID on file · 206 papers in corpus · active 2002-2026

Study types

  • article 115
  • other 24
  • review 23
  • preprint 10
  • meta-analysis 4

Condition tags

  • endometriosis 180
  • infertility 22
  • chronic_pelvic_pain 7
  • adenomyosis 5
  • dysmenorrhea 4
  • irritable_bowel_syndrome 3
  • die_deep_infiltrating 2
  • endometrioma 1
other 2023
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2023.07.033

BACKGROUND: Endometriosis has been linked to higher rates of a variety of symptoms; however, the findings from longitudinal studies are scarce and inconsistent. OBJECTIVE: This study aimed to examine the association between endometriosis a…

article 2023
Reproduction & fertility ·doi:10.1530/raf-23-0014

Endometriosis is a common yet under-recognised chronic inflammatory disease, affecting 176 million women, trans and gender diverse people globally. The National Endometriosis Clinical and Scientific Trials (NECST) Registry is a new clinical…

article 2023
Cell reports. Medicine ·doi:10.1016/j.xcrm.2023.101250

In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed. Using large-scale datasets, we report a genetic correlation between endometriosis and irritable bowel syndrome (IBS), peptic ulcer dise…

article 2023
BMC medicine ·doi:10.1186/s12916-023-03166-1

BACKGROUND: Endometriosis is a common, gynaecological disease characterised by the presence of endometrial-like cells growing outside the uterus. Lesions appear at multiple locations, present with variation in appearance, size and depth of …

book-chapter 2023
·doi:10.1016/b978-0-323-91380-5.00018-6
article 2023
Human genetics ·doi:10.1007/s00439-023-02582-w

Comorbid conditions can be driven by underlying pleiotropic and causal mechanisms that can provide insights into shared molecular and biological processes contributing to disease risk. Endometriosis is a chronic condition affecting one in n…

article 2023
Cells ·doi:10.3390/cells12131736

Identifying tissue-specific molecular signatures of active regulatory elements is critical to understanding gene regulatory mechanisms. In this study, transcription start sites (TSS) and enhancers were identified using Cap analysis of gene …

article 2023
Communications biology ·doi:10.1038/s42003-023-05070-z

Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Herein, we characterize variation in DNA methylation (DNAm) and its association with menstrual cycle phase, endometriosis, and genetic variants t…

article 2023
Maturitas ·doi:10.1016/j.maturitas.2023.04.272

OBJECTIVE: To examine the association between endometriosis and women's health-related quality of life (HRQoL). STUDY DESIGN: This study included 3728 women born in 1973-78 using data from the Australian Longitudinal Study on Women's Healt…

review 2023
Human reproduction update ·doi:10.1093/humupd/dmad009

BACKGROUND: Endometriosis remains a poorly understood disease, despite its high prevalence and debilitating symptoms. The overlap in symptoms and the increased risk of multiple other traits in women with endometriosis is becoming increasing…

article 2023
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15549

Endometriosis is a serious, chronic disorder where endometrial tissue grows outside the uterus, causing severe pelvic pain and infertility. It affects 11% of women. Endometriosis is a multifactorial disorder of unclear etiology, although re…

article 2023
·doi:10.1016/j.cdnut.2023.101350
article 2023
BMC medicine ·doi:10.1186/s12916-023-03184-z

BACKGROUND: Endometriosis affects 1 in 9 women, yet it is poorly understood with long diagnostic delays, invasive diagnoses, and poor treatment outcomes. Characterised by the presence of endometrial-like tissue outside of the uterus, its ma…

other 2023
·doi:10.6084/m9.figshare.c.6965020.v1

Abstract Background Endometriosis affects 1 in 9 women, yet it is poorly understood with long diagnostic delays, invasive diagnoses, and poor treatment outcomes. Characterised by the presence of endometrial-like tissue outside of the uterus…

other 2023
·doi:10.6084/m9.figshare.c.6965020

Abstract Background Endometriosis affects 1 in 9 women, yet it is poorly understood with long diagnostic delays, invasive diagnoses, and poor treatment outcomes. Characterised by the presence of endometrial-like tissue outside of the uterus…

meta-analysis 2023
Nature genetics ·doi:10.1038/s41588-023-01323-z

Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genom…

article 2022
Communications biology ·doi:10.1038/s42003-022-03541-3

Cellular development is tightly regulated as mature cells with aberrant functions may initiate pathogenic processes. The endometrium is a highly regenerative tissue, shedding and regenerating each month. Endometrial stromal fibroblasts are …

meta-analysis 2022
Cell reports. Medicine ·doi:10.1016/j.xcrm.2022.100542

Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Using data from large endometriosis and EOC genome-wide association meta-analyses, we estimate the genetic correlation and evaluate the causal relationshi…

erratum 2022
Nature communications ·doi:10.1038/s41467-022-33222-y
article 2022
Obesity research & clinical practice ·doi:10.1016/j.orcp.2022.04.002

BackgroundWomen with lower body mass index (BMI) have a higher risk of surgically confirmed endometriosis but this finding runs counterintuitive to the oestrogen-dependent theory for the disease. Increasingly, endometriosis is diagnosed via…

article 2022
International Journal of Gynecology & Obstetrics ·doi:10.1002/ijgo.14115

OBJECTIVE: To study clinical, surgical characteristics and the relationship between endometriosis lesion types and conception rate after surgery in infertile women with endometriosis. METHODS: A prospective, multicenter cohort of 204 women …

article 2022
BMJ open ·doi:10.1136/bmjopen-2022-064333

PURPOSE: Previous studies have identified associations between individual reproductive factors and chronic disease risk among postmenopausal women. However, few have investigated the association of different markers of reproductive function…

preprint 2022
·doi:10.1101/2022.10.20.22281201

Abstract In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed; however, the factors driving this link remain largely unknown. Here, using large-scale multifaceted data including observation…

other 2022
Scientific reports ·doi:10.1038/s41598-022-13488-4

Endocannabinoids mediate cellular functions and their activity is controlled by a complex system of enzymes, membrane receptors and transport molecules. Endocannabinoids are present in endometrium, a cyclical regenerative tissue requiring t…

review 2022
Frontiers in reproductive health ·doi:10.3389/frph.2021.795464

The endometrium is a complex and dynamic tissue essential for fertility and implicated in many reproductive disorders. The tissue consists of glandular epithelium and vascularised stroma and is unique because it is constantly shed and regro…