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Author Correction: Genome-wide association and epidemiologi-
cal analyses reveal common genetic origins between uterine
leiomyomata and endometriosis
C. S. Gallagher, N. Mäkinen, H. R. Harris, N. Rahmioglu, O. Uimari ,J .P .C o o k ,
N .S h i g e s i ,T .F e r r e i r a ,D .R .V e l e z - E d w a r d s ,T .L .E d w a r d s,S .M o r t l o c k ,
Z. Ruhioglu ,F .D a y ,C .M .B e c k e r , V. Karhunen, H. Martikainen, M.-
R. Järvelin ,R .M .C a n t o r ,P .M .R i d k e r ,K .L .T e r r y ,J .E .B u r i n g ,S .D .G o r d o n,
S. E. Medland ,G .W .M o n t g o m e r y,D .R .N y h o l t ,D .A .H i n d s ,J .Y .T u n g ,
t h e2 3 a n d M eR e s e a r c hT e a m * ,J .R .B .P e r r y ,P .A .L i n d,J .N .P a i n t e r ,
N. G. Martin , A. P. Morris, D. I. Chasman, S. A. Missmer, K. T. Zondervan &
C. C. Morton
The original version of this Article contained an error in Table1,i nw h i c ht h eo d d sr a t i o sw e r e
incorrectly calculated. The correct version of Table1 is:
Table 1 | Overview of lead SNPs with significant associations at 29 independent loci in UL GWAS meta-analysis
Locus Lead SNP RA OA RAF EUR PMeta OR (95% CI) Gene(s) of interest a
1p36.12b,c rs7412010 C G 0.15 2.4 × 10 −29 1.13 (1.11–1.16) WNT4, CDC42
2p23.2 rs55819434 A G 0.91 5.6 × 10 −09 0.92 (0.90–0.95) BABAM2
2p25.1b,c rs35417544 T C 0.69 2.3 × 10 −19 1.09 (1.07–1.10) GREB1
3q26.2c rs35446936 A G 0.24 1.0 × 10 −08 0.95 (0.93–0.96) TERC
4q12c rs62323682 T C 0.94 4.9 × 10 −18 0.87 (0.84–0.90) LNX1, PDGFRA
4q13.3c rs12640488 A G 0.52 4.0 × 10 −14 0.94 (0.92–0.96) SULT1B1
4q22.3 rs4699299 T C 0.69 4.7 × 10 −08 0.95 (0.94–0.97) PDLIM5
5p15.33c rs72709458 T C 0.23 4.7 × 10 −21 1.10 (1.08–1.13) TERT
5q35.2c rs2456181 C G 0.49 1.1 × 10 −11 0.94 (0.93–0.96) ZNF346, UIMC1
6p21.31 rs116251328 A T 0.02 3.0 × 10 −08 1.15 (1.09–1.21) GRM4, HMGA1
6q25.2b,c rs58415480 C G 0.84 1.9 × 10 −54 0.84 (0.82–0.86) SYNE1, ESR1
7q31.2 rs2270206 A C 0.16 4.6 × 10 −08 1.06 (1.04–1.09) WNT2
9p24.3c rs10976689 A G 0.60 2.4 × 10 −13 0.94 (0.93–0.96) ANKRD15
10q24.3c rs9419958 T C 0.13 1.1 × 10 −16 1.10 (1.08–1.13) OBFC1, SLK
10p11.22 rs10508765 A G 0.80 1.5 × 10 −10 1.07 (1.05–1.09) ZEB1, ARHGAP12
11p15.5c rs547025 T C 0.92 1.5 × 10 −14 1.13 (1.09–1.16) RIC8A, BET1L
11p14.1b rs11031006 A G 0.14 5.7 × 10 −15 0.91 (0.89–0.93) FSHB
11p13c rs61889186 C G 0.86 1.4 × 10 −25 0.89 (0.87–0.91) WT1
11p13c rs2785202 C G 0.55 6.9 × 10 −14 1.06 (1.05–1.08) PDHX, CD44
11q22.3c rs149934734 T C 0.03 1.1 × 10 −27 1.33 (1.26–1.40) C11orf65, KDELC2
12q13.11c rs2131371 A C 0.28 1.6 × 10 −18 0.93 (0.91–0.94) SLC38A2
12q15 rs11178393 T C 0.89 3.3 × 10 −08 1.08 (1.05–1.10) PTPRR
12q24.31 rs28583837 A G 0.22 2.3 × 10 −08 0.94 (0.92–0.96) PITPNM2
13q14.11c rs117245733 A G 0.02 5.7 × 10 −14 1.31 (1.21–1.39) FOXO1
17p13.1c rs78378222 T G 0.99 7.1 × 10 −31 0.65 (0.60–0.70) SHBG, TP53
20p12.3c rs16991615 A G 0.07 8.8 × 10 −10 1.11 (1.07–1.14) MCM8, TRMT6
22q13.1c rs4821939 A T 0.20 7.8 × 10 −16 1.08 (1.06–1.10) TNRC6B
Xp26.2c rs12392108 A T 0.31 5.9 × 10 −46 1.13 (1.11–1.15) RAP2C
Xq13.1c rs4360450 A G 0.37 2.1 × 10 −18 1.08 (1.06–1.10) MED12
SNP single-nucleotide polymorphism,RA risk allele, OA other allele, RAFEUR average risk allele frequency in European samples,OR odds ratio
a≤300 kb distant from association signal
bLoci previously associated with endometriosis
cLoci previously associated with UL
Correction to:Nature Communications
https://doi.org/10.1038/s41467-019-12536-4,
published online 24 October 2019
https://doi.org/10.1038/s41467-022-33222-y
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nature communications (2022) 13:5543 | 1
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Table 1 | Overview of lead SNPs with significant associations at 29 independent loci in UL GWAS meta-analysis
Locus Lead SNP RA OA RAF EUR PMeta OR (95% CI) Gene(s) of interest a
1p36.12b,c rs7412010 C G 0.15 2.4 × 10 −29 1.13 (1.11–1.16) WNT4, CDC42
2p23.2 rs55819434 A G 0.91 5.6 × 10 −09 1.09 (1.06–1.12) BABAM2
2p25.1b,c rs35417544 T C 0.69 2.3 × 10 −19 1.09 (1.07–1.10) GREB1
3q26.2c rs35446936 A G 0.24 1.0 × 10 −08 1.06 (1.04–1.08) TERC
4q12c rs62323682 T C 0.94 4.9 × 10 −18 1.15 (1.12–1.19) LNX1, PDGFRA
4q13.3c rs12640488 A G 0.52 4.0 × 10 −14 1.06 (1.05–1.08) SULT1B1
4q22.3 rs4699299 T C 0.69 4.7 × 10 −08 1.05 (1.03–1.07) PDLIM5
5p15.33c rs72709458 T C 0.23 4.7 × 10 −21 1.10 (1.08–1.13) TERT
5q35.2c rs2456181 C G 0.49 1.1 × 10 −11 1.06 (1.04–1.08) ZNF346, UIMC1
6p21.31 rs116251328 A T 0.02 3.0 × 10 −08 1.15 (1.09–1.21) GRM4, HMGA1
6q25.2b,c rs58415480 C G 0.84 1.9 × 10 −54 1.19 (1.17–1.22) SYNE1, ESR1
7q31.2 rs2270206 A C 0.16 4.6 × 10 −08 1.06 (1.04–1.09) WNT2
9p24.3c rs10976689 A G 0.60 2.4 × 10 −13 1.06 (1.05–1.08) ANKRD15
10q24.3c rs9419958 T C 0.13 1.1 × 10 −16 1.10 (1.08–1.13) OBFC1, SLK
10p11.22 rs10508765 A G 0.80 1.5 × 10 −10 1.07 (1.05–1.09) ZEB1, ARHGAP12
11p15.5c rs547025 T C 0.92 1.5 × 10 −14 1.13 (1.09–1.16) RIC8A, BET1L
11p14.1b rs11031006 A G 0.14 5.7 × 10 −15 1.10 (1.07–1.12) FSHB
11p13c rs61889186 C G 0.86 1.4 × 10 −25 1.12 (1.10–1.15) WT1
11p13c rs2785202 C G 0.55 6.9 × 10 −14 1.06 (1.05–1.08) PDHX, CD44
11q22.3c rs149934734 T C 0.03 1.1 × 10 −27 1.33 (1.26–1.40) C11orf65, KDELC2
12q13.11c rs2131371 A C 0.28 1.6 × 10 −18 1.08 (1.06–1.10) SLC38A2
12q15 rs11178393 T C 0.89 3.3 × 10 −08 1.08 (1.05–1.10) PTPRR
12q24.31 rs28583837 A G 0.22 2.3 × 10 −08 1.06 (1.04–1.08) PITPNM2
13q14.11c rs117245733 A G 0.02 5.7 × 10 −14 1.31 (1.21–1.39) FOXO1
17p13.1c rs78378222 T G 0.99 7.1 × 10 −31 1.54 (1.43–1.66) SHBG, TP53
20p12.3c rs16991615 A G 0.07 8.8 × 10 −10 1.11 (1.07–1.14) MCM8, TRMT6
22q13.1c rs4821939 A T 0.20 7.8 × 10 −16 1.08 (1.06–1.10) TNRC6B
Xp26.2c rs12392108 A T 0.31 5.9 × 10 −46 1.13 (1.11–1.15) RAP2C
Xq13.1c rs4360450 A G 0.37 2.1 × 10 −18 1.08 (1.06–1.10) MED12
SNP single-nucleotide polymorphism,RA risk allele, OA other allele, RAFEUR average risk allele frequency in European samples,OR odds ratio
a≤300 kb distant from association signal
bLoci previously associated with endometriosis
cLoci previously associated with UL
Corrections & amendments
nature communications (2022) 13:5543 | 2
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