Body mass index and the diagnosis of endometriosis: Findings from a national data linkage cohort study
This study found that weight gain after young adulthood was associated with a lower risk of surgically confirmed endometriosis, while being overweight in young adulthood was linked to a higher risk of physician-diagnosed endometriosis.
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This national data linkage cohort study analyzed 11,794 Australian women (born 1989–95) who completed six surveys between 2013 and 2018, with survey data linked to administrative health records to identify endometriosis. Using Cox proportional hazards models, it assessed BMI at ages 18–23 and subsequent BMI change, stratifying outcomes by diagnostic method: clinically confirmed endometriosis from hospital discharge diagnoses versus clinically suspected endometriosis based on women’s reports of physician-diagnosed disease. Women who gained weight after ages 18–23 had a lower risk of clinically confirmed endometriosis (HR 0.64, 95% CI 0.47–0.88), while overweight at 18–23 was associated with a higher risk of clinically suspected endometriosis (HR 1.29, 95% CI 1.01–1.66). This paper is centrally about endometriosis — it examines how BMI and weight change relate to endometriosis risk across confirmed and suspected diagnostic pathways.
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Cited by (11)
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- Uncovering Symptom-Lesion Associations Through Machine Learning 2025
- Is the leptin/BMI ratio a reliable biomarker for endometriosis? 2024
- The Molecular Link between Obesity and the Endometrial Environment: A Starting Point for Female Infertility 2024
- A Comprehensive Review of Advanced Diagnostic Techniques for Endometriosis: New Approaches to Improving Women’s Well-Being 2024
- Association between exposure to perfluoroalkyl substances (PFAS) and endometriosis in the ENDEA case-control study 2024
- Association between urinary concentrations of polycyclic aromatic hydrocarbons and risk of endometriosis in the NHANES 2003–2006 2023
- A Life Course Approach to Endometriosis 2023
- An insight into gut microbiota and metabolites in the mice with adenomyosis 2023
- Height and pelvic lesion number: Do they have a positive relationship with postoperative recurrence in adolescent endometriosis?—A retrospective clinical analysis of 89 adolescent endometriosis in China 2022
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