Ali Akoum

No ORCID on file · 88 papers in corpus · active 1995-2016

Study types

  • article 57
  • dataset 20
  • other 8
  • book-chapter 1
  • reference-entry 1

Condition tags

  • endometriosis 82
  • infertility 9
  • chronic_pelvic_pain 5
  • dysmenorrhea 1
  • endometrioma 1
  • dyspareunia 1
article 2001
Correlation Between Decreased Type‐II Interleukin‐1 Receptor and Increased Monocyte Chemotactic Protein‐1 Expression in the Endometrium of Women with Endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.8755-8920.2001.450401.x

PROBLEM: Monocyte chemotactic protein-1 (MCP-1), a potent inducer of macrophage recruitment and activation, is overexpressed in the eutopic endometrium of women with endometriosis. Eutopic endometrial cells of women with endometriosis secre…

article 2001
Decreased Expression of the Decoy Interleukin-1 Receptor Type II in Human Endometriosis
The American journal of pathology ·doi:10.1016/s0002-9440(10)63990-9
article 2001
Ectopic endometrial cells express high concentrations of interleukin (IL)-8 in vivo regardless of the menstrual cycle phase and respond to oestradiol by up-regulating IL-1-induced IL-8 expression in vitro
Molecular human reproduction ·doi:10.1093/molehr/7.9.859

Endometriosis, an oestrogen-dependent disorder affecting women of reproductive age, is associated with active angiogenesis and an increased recruitment of leukocyte into the peritoneal cavity where the implants often develop. The role of oe…

article 2000
Effect of hormonal agents on monocyte chemotactic protein-1 expression by endometrial epithelial cells of women with endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(00)01540-5
article 2000
Estradiol Amplifies Interleukin-1-Induced Monocyte Chemotactic Protein-1 Expression by Ectopic Endometrial Cells of Women with Endometriosis
·doi:10.1210/jc.85.2.896
article 2000
Estradiol Amplifies Interleukin-1-Induced Monocyte Chemotactic Protein-1 Expression by Ectopic Endometrial Cells of Women with Endometriosis1
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.2.6348

Endometriosis, one of the most frequently occurring gynecological disorders, is estrogen dependent and is often associated with immunological changes. These include increased macrophage activation and infiltration into the endometriotic imp…

article 1999
Immunohistochemical localization of insulin-like growth factor–binding protein-3 in eutopic and ectopic endometrial tissues
Fertility and Sterility ·doi:10.1016/s0015-0282(99)00443-4
article 1999
Physiological and Cytogenetic Characterization of Immortalized Human Endometriotic Cells Containing Episomal Simian Virus 40 DNA
The American journal of pathology ·doi:10.1016/s0002-9440(10)65376-x
article 1997
O-037 Increased expression of monocyte chemotactic protein-1 in the endometrium of women with endometriosis
·doi:10.1016/s0015-0282(97)90669-5
article 1996
Endometriosis: Secretion of interleukin-6 by human endometriotic cells and regulation by proinflammatory cytokines and sex steroids
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a019088

Endometriosis is generally associated with an immunoinflammatory process that takes place in the peritoneal cavity of patients. Interleukin (IL)-6, a multifunctional cytokine involved in numerous immunological and proliferative processes, h…

article 1996
Increased monocyte chemotactic protein-1 level and activity in the peripheral blood of women with endometriosis
American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(96)70115-1
article 1995
Cytokine-induced secretion of monocyte chemotactic protein-1 by human endometriotic cells in culture
American Journal of Obstetrics and Gynecology ·doi:10.1016/0002-9378(95)90578-2
article 1995
N-terminal truncated forms of insulin-like growth factor binding protein-3 in the peritoneal fluid of women without laparoscopic evidence of endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)57362-2