Kettel LM

No ORCID on file · 9 papers in corpus · active 1989-1998

Study types

  • article 4
  • review 3
  • case-report 1
  • other 1

Condition tags

  • endometriosis 9
  • chronic_pelvic_pain 1
  • infertility 1
case-report 1998
Preliminary report on the treatment of endometriosis with low-dose mifepristone (RU 486)
American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(98)70316-3

OBJECTIVE: We have previously shown that treatment with mifepristone, 50 to 100 mg daily, results in amenorrhea, anovulation, and symptomatic improvement in women with endometriosis. In this study we lowered the dose to 5 mg daily to determ…

review 1997
MODERN MEDICAL MANAGEMENT OF ENDOMETRIOSIS
Obstetrics and gynecology clinics of North America ·doi:10.1016/s0889-8545(05)70309-0

The modern medical management of endometriosis has changed considerably since the first attempts were made to control this disease hormonally over four decades ago. Currently, there are multiple choices for the clinician and patient, includ…

review 1996
Mifepristone: Clinical Application in General Gynecology
Clinical obstetrics and gynecology ·doi:10.1097/00003081-199606000-00018

RU-486, the first clinically available antiprogestin, has numerous gynecologic applications beyond first-trimester pregnancy termination. Long-term administration of 2 mg/day of RU-486 suppresses ovulation while maintaining serum estrogen l…

other 1996
Treatment of endometriosis with the antiprogesterone mifepristone (RU486)
Fertility and Sterility ·doi:10.1016/s0015-0282(16)58022-4

OBJECTIVE: To evaluate the safety and efficacy of an antiprogesterone (mifepristone, RU486; Roussel-Uclaf, Romaineville, France) on endometriosis. DESIGN: An open, prospective clinical trial. SETTING: The clinical practice of an academic …

review 1995
Clinical applications of the antiprogestins
Clinical obstetrics and gynecology ·doi:10.1097/00003081-199538040-00026
article 1995
Endometrial effects of long-term low-dose administration of RU486
Fertility and Sterility ·doi:10.1016/s0015-0282(16)57478-0

ObjectiveTo examine endometrial response to long-term low-does RU486 administration.DesignRetrospective controlled study of women with endometriosis treated for 6 months with 50 mg RU486 daily for 6 months. Controls consisted of women in th…

article 1994
Clinical efficacy of the antiprogesterone RU486 in the treatment of endometriosis and uterine fibroids
Human Reproduction ·doi:10.1093/humrep/9.suppl_1.116

To evaluate the long-term effects of treatment with RU486 and to test its efficacy in endometriosis, a 3-month trial was conducted to evaluate the effects of daily administration (100 mg/day or approximately 2 mg/kg/day) on the functional a…

article 1991
Endocrine responses to long-term administration of the antiprogesterone RU486 in patients with pelvic endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)54531-2

ObjectiveTo examine endocrine and clinical responses to long-term administration of RU486 in patients with endometriosis.DesignProspective open trial.SettingFaculty practice of the authors.Patients, participantsSix normally cycling women wi…

article 1989
Combination medical and surgical therapy for infertile patients with endometriosis.
Obstetrics and gynecology clinics of North America

Endometriosis is a difficult problem for practicing gynecologists and is commonly associated with infertility. The diagnosis of endometriosis should only be made at the time of laparoscopy or laparotomy and should be confirmed with biopsy i…