Yen SS

No ORCID on file · 9 papers in corpus · active 1971-2008

Study types

  • article 4
  • case-report 1
  • other 1
  • review 1

Condition tags

  • endometriosis 7
  • chronic_pelvic_pain 1
article 2008
Suppression of Gonadotropins and Estradiol in Premenopausal Women by Oral Administration of the Nonpeptide Gonadotropin-Releasing Hormone Antagonist Elagolix
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2008-1695

CONTEXT: Parenteral administration of peptide GnRH analogs is widely employed for treatment of endometriosis and fibroids and in assisted-reproductive therapy protocols. Elagolix is a novel, orally available nonpeptide GnRH antagonist. OBJE…

case-report 1998
Preliminary report on the treatment of endometriosis with low-dose mifepristone (RU 486)
American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(98)70316-3

OBJECTIVE: We have previously shown that treatment with mifepristone, 50 to 100 mg daily, results in amenorrhea, anovulation, and symptomatic improvement in women with endometriosis. In this study we lowered the dose to 5 mg daily to determ…

other 1996
Treatment of endometriosis with the antiprogesterone mifepristone (RU486)
Fertility and Sterility ·doi:10.1016/s0015-0282(16)58022-4

OBJECTIVE: To evaluate the safety and efficacy of an antiprogesterone (mifepristone, RU486; Roussel-Uclaf, Romaineville, France) on endometriosis. DESIGN: An open, prospective clinical trial. SETTING: The clinical practice of an academic …

article 1995
Endometrial effects of long-term low-dose administration of RU486
Fertility and Sterility ·doi:10.1016/s0015-0282(16)57478-0

ObjectiveTo examine endometrial response to long-term low-does RU486 administration.DesignRetrospective controlled study of women with endometriosis treated for 6 months with 50 mg RU486 daily for 6 months. Controls consisted of women in th…

article 1994
Clinical efficacy of the antiprogesterone RU486 in the treatment of endometriosis and uterine fibroids
Human Reproduction ·doi:10.1093/humrep/9.suppl_1.116

To evaluate the long-term effects of treatment with RU486 and to test its efficacy in endometriosis, a 3-month trial was conducted to evaluate the effects of daily administration (100 mg/day or approximately 2 mg/kg/day) on the functional a…

article 1991
Endocrine responses to long-term administration of the antiprogesterone RU486 in patients with pelvic endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)54531-2

ObjectiveTo examine endocrine and clinical responses to long-term administration of RU486 in patients with endometriosis.DesignProspective open trial.SettingFaculty practice of the authors.Patients, participantsSix normally cycling women wi…

1989
Chronic inhibition of hypothalamic-pituitary-ovarian axis and body weight gain by brain-directed delivery of estradiol-17 beta in female rats.
Neuroendocrinology ·doi:10.1159/000125223

The effect of preferential delivery of estradiol (E2) into the brain on both the hypothalamic-pituitary-ovarian axis and weight gain was studied in female rats. When E2 was coupled to a lipoidal dihydropyridine-pyridinium carrier, the resul…

review 1983
Clinical applications of gonadotropin-releasing hormone and gonadotropin-releasing hormone analogs
Fertility and Sterility
1971
The effect of ovariectomy on gonadotropin release.
The Journal of clinical investigation ·doi:10.1172/jci106587

The sequential changes in the concentration and pattern of circulating luteinizing hormone (LH) and follicle-stimulating hormone (FSH)(1) following bilateral ovariectomy were determined in 10 premenopausal women. The initial (1st wk) and de…