Chapter 1 1.1 Chapter 1 13.2.2Ce// actf?es/on mo/eci//es Adhesive properties of endometrial cells determine the process of attachment of retrogradely shed endometrium to the peritoneal lining.Several cell adhesion molecules are expressed by…
Our recent DNA microarray analysis using tissue obtained by laser capture microdissection (LCM) identified up-regulation of RON (a tyrosine kinase receptor) during the late secretory phase in eutopic endometrial epithelial cells from patien…
Endometriosis, a common gynecological disorder that causes infertility and pelvic pain, is defined as the presence of endometrial glands and stroma within extra-uterine sites. However, despite extensive studies its etiology and pathogenesis…
BACKGROUND: Recent studies have indicated new physiological roles for erythropoietin (Epo) unrelated to erythropoiesis. We previously demonstrated that the Epo concentrations in peritoneal fluid from patients with stage I endometriosis were…
Erythropoietin (Epo) is an important regulator of erythropoiesis and stimulates the proliferation of early erythroid precursors as well as the differentiation of late erythroid precursors of the erythroid lineage. However, recent studies ha…
ObjectiveTo quantify and compare messenger RNA (mRNA) levels of ER-alpha and ER-beta among ovarian endometriotic cysts and red and black peritoneal endometriotic lesions.DesignProspective study.SettingUniversity hospital.Patient(s)Patients …
ObjectiveThis study was undertaken to evaluate the immunohistochemical expression of the cell cycle inhibitor p27Kip1 and proliferation marker Ki67 in peritoneal endometriosis and eutopic endometrium.DesignProspective study.SettingUniversit…
A 21-year-old-woman had a double uterus with noncommunicating right uterine horn and communicating left uterine horn. The pelvic cavity showed evidence of endometriosis and adhesions from previous laparotomy. A finger was inserted under lap…
ObjectiveTo investigate the angiogenic status of the vasculature in peritoneal endometriosis based on macroscopic appearance.DesignProspective study.SettingUniversity hospital.Patient(s)Patients with peritoneal endometriosis.Intervention(s)…
ObjectiveTo quantify messenger RNA (mRNA) levels of the two estrogen receptor isoforms, estrogen receptor-alpha (ER-alpha) and estrogen receptor-beta (ER-beta) in the eutopic endometrium and ovarian endometriotic cysts.DesignProspective stu…