Kim H

The female reproductive system, including the endometrium, placenta, ovary, cervix, and fallopian tube, plays a critical role in conception, implantation, and fetal development. Recent advances in bioengineered models such as organoids, org…

Background/Objectives: The treatment options for endometriosis vary depending on individual needs and clinical circumstances. To preserve ovarian reserve, ethanol catheter-directed sclerotherapy may be considered as a treatment option. We c…

BackgroundEndometrial cancer (ECa) is one of the most common gynecologic malignancies, with limited therapeutic responses in metastatic or recurrent cases. The bacterial microbiota has emerged as a key modulator of carcinogenesis and antitu…

Hwawon Lim,1 Yumi Shin,1 Hyunjo Kim,2 Bo Young Choi,1 Jee Yoon Park,1,3 Jae-Young Lim,2,4 Pyung-Bok Lee5 1Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; 2Department of Rehab…

OBJECTIVE: To assess the associations of time to endometriosis diagnosis after presentation for pelvic pain between patients of different ages, races, ethnicities, and body mass index (BMI) ranges. METHODS: This retrospective study was con…

PurposeTo investigate whether the number of oocytes retrieved after controlled ovarian stimulation (COS) for fertility preservation (FP) can be predicted using serum anti-Müllerian hormone (AMH) levels in adolescent and young adult (AYA) wo…

In mice, the uterus undergoes dynamic changes regulated by estrogen and progesterone during the estrous cycle. Proper regulation of these changes is critical for successful pregnancy. The Family with sequence similarity 3 (Fam3) gene family…

ObjectivesAlthough particulate matter (PM) exposure poses significant public health risks, previous research has focused on limited clinical areas. However, emerging evidence and pathological mechanisms of PM suggest that PM may exert broad…

The association between uterine leiomyoma and migraine is unknown. This study aimed to explore the risk of uterine leiomyoma among women with migraine in reproductive age (i.e., 20-39 years). Using the Korean National Health Insurance Servi…

Background/Objectives: The prognosis of endometriosis-related ovarian clear cell carcinoma (OCCC) versus non-endometriosis-associated OCCC remains unclear. We examined the impact of endometriosis on OCCC diagnosis and progression and assess…

Primary dysmenorrhea (PD) is characterized by excessive uterine contraction and ischemic vasoconstriction, primarily driven by elevated levels of prostaglandins (PGs; PGF2α) and inflammatory mediators. Nonsteroidal antiinflammatory drugs (N…

BackgroundThe relationship between COVID-19 vaccines and menstrual disturbance is unclear, in part because researchers have measured different outcomes (e.g., delays vs. changes to cycle length) with various study designs. Menstrual disrupt…

Background and Objectives: This systematic review and network meta-analysis evaluated the effects of postoperative opioid use on nausea and vomiting in women undergoing laparoscopic hysterectomy. Materials and Methods: A systematic search o…

BackgroundThe oocyte retrieval is a critical step in assisted reproductive technologies, including in vitro fertilization and fertility preservation. Despite evolving techniques, the optimal aspiration pressure during retrieval remains deba…

ImportanceEmbryo implantation is a hormone-regulated event requiring a receptive endometrium. In vitro models that simulate this process are essential for studying early embryonic development. Endometrial epithelial organoids (EEOs) provide…

Type 2 innate lymphoid cells (ILC2s) are an important source of innate cytokines that contribute to allergic inflammation. Recent studies have also suggested that ILC2s play a biological role in peripheral tissues such as lung, fat, intesti…

OBJECTIVE: To describe the incidence of uterovaginal anomalies and histologic findings in transgender and nonbinary (TGNB) patients seeking hysterectomies. METHODS: All patients receiving gender-affirming hysterectomies between 2013 and 20…

Background and Objectives: Autonomic nervous system (ANS) disorders are responsible for primary dysmenorrhea and are closely linked to the spine. This study aims to evaluate the effects of sacroiliac joint manipulation on the ANS and lower …

The Gfo/Idh/MocA family enzyme DgpA was known to catalyze the regiospecific oxidation of puerarin to 3"-oxo-puerarin in the presence of 3-oxo-glucose. Here, we discovered that D3dgpA, dgpA cloned from the human gut bacterium Dorea sp. MRG-I…

PURPOSE: To determine whether patients with Marfan syndrome are at an increased risk for reproductive disorders. METHODS: This retrospective cohort study was conducted using the US collaborative network on the TriNetX research network of h…

PurposeMultifetal gestation (MFG) is much more common in pregnancies that utilize assisted reproductive technologies (ART). We assessed how these rates have changed over the previous decade and the impact on live birth rates (LBR).MethodsTh…

This study aimed to investigate the efficacy and safety of using optimized parameters obtained by computer simulation for ultrasound-guided high-intensity focused ultrasound (HIFU) treatment of uterine adenomyosis in comparison with convent…

Oral administration facilitates the direct delivery of drugs to lesions within the small intestine and colon, making it an ideal approach for treating patients with inflammatory bowel disease. However, multiple physical barriers impede the …

The prevalence of genital human papillomavirus (HPV) in women with endometriosis has never been reported in a national representative survey. We aimed to investigate the association of endometriosis with the prevalence of HPV. We analyzed t…