Fazleabas AT

No ORCID on file · 85 papers in corpus · active 1987-2026

Study types

  • article 46
  • other 15
  • review 10
  • preprint 1

Condition tags

  • endometriosis 70
  • infertility 29
  • chronic_pelvic_pain 8
  • die_deep_infiltrating 2
  • adenomyosis 2
other 2006
Induced endometriosis in the baboon (Papio anubis) increases the expression of the proangiogenic factor CYR61 (CCN1) in eutopic and ectopic endometria
Biology of reproduction ·doi:10.1095/biolreprod.105.049320

The expression of human CYR61 (cysteine-rich, angiogenic inducer, 61; CCN1) mRNA has been previously shown to be deregulated in the endometrium of women with endometriosis. We have chosen the baboon model (Papio anubis) of induced endometri…

article 2006
Morphological and glycosylation changes associated with the endometrium and ectopic lesions in a baboon model of endometriosis
Human Reproduction ·doi:10.1093/humrep/del310

BACKGROUND: Endometriosis is one of the most common causes of infertility and pelvic pain. A baboon model has recently been developed whereby the intrapelvic injection of menstrual endometrium results in the induction of endometriotic lesio…

article 2006
The Estrogen Early Response Gene FOS Is Altered in a Baboon Model of Endometriosis1
Biology of reproduction ·doi:10.1095/biolreprod.106.052852

Endometriosis, the presence of a functional endometrium outside of the uterine cavity, is associated with infertility. In our simulated model of pregnancy in baboons with experimental endometriosis, hCG infusion fails to induce expression o…

article 2005
A Baboon Model for Inducing Endometriosis
Methods in molecular medicine ·doi:10.1385/1-59259-983-4:093

Endometriosis is a disease that is associated with severe pelvic pain and is a major cause of infertility in women. It is an enigmatic disease whose etiology and pathophysiology has been studied to a limited extent. The events associated wi…

article 2004
Endometriosis in the baboon.
Gynecologic and obstetric investigation
review 2004
Uterine receptivity and implantation: The regulation and action of insulin-like growth factor binding protein-1 (IGFBP-1), HOXA10 and forkhead transcription factor-1 (FOXO-1) in the baboon endometrium
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-2-34

In primates, the phase of the menstrual cycle when the uterus becomes receptive is initially dependent on estrogen and progesterone. Further morphological and biochemical changes are induced as a result of biochemical signals between the em…

review 2003
Future directions in endometriosis research
Seminars in reproductive medicine ·doi:10.1055/s-2003-41331

Endometriosis is an estrogen-dependent condition that affects 5 million American women; however, its etiology is not fully understood. The development of the baboon model of endometriosis provides an extremely powerful tool to investigate t…

article 2003
Steroid receptor and aromatase expression in baboon endometriotic lesions
Fertility and Sterility ·doi:10.1016/s0015-0282(03)00982-8

ObjectiveTo evaluate steroid receptor and aromatase gene expression in endometriotic lesions, and determine the effects of endometriosis on uterine receptivity in a baboon model for endometriosis.DesignProspective study to determine the exp…

review 2002
A Modified Baboon Model for Endometriosis
Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.2002.tb02791.x

Endometriosis is one of the most common causes of infertility and chronic pelvic pain and affects 1 in 10 women in the reproductive-age group. Although existence of this disease has been known for over 100 years, our current knowledge of it…

article 1987
Protein, progesterone, and protease inhibitors in uterine and peritoneal fluids of women with endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)49994-2

This study was undertaken to determine whether women with endometriosis have altered protein, progesterone (P), and protease inhibitor concentrations in their uterine fluid and peritoneal fluid (PF) compared with controls at different phase…