Michele G da Broi

No ORCID on file · 7 papers in corpus
other 2021
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2021.01.024

RESEARCH QUESTION: Is the transcriptome of cumulus cells of infertile women with advanced endometriosis (EIII/IV), with and without endometrioma, altered? DESIGN: In this prospective case-control study, next-generation RNA sequencing was u…

observational 2017
JBRA assisted reproduction ·doi:10.5935/1518-0557.20170038

OBJECTIVE: Alterations in endometrial receptivity may be involved in the etiopathogenesis of endometriosis-related infertility. The literature has suggested that patients with endometriosis present progestin resistance, which could affect e…

observational 2017
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2017.06.021

A deleterious effect of endometriosis on oocyte quality has been proposed. Evidence suggests that cumulus cells could be used as indirect biomarkers of oocyte quality. The PTGS2 gene, which encodes cyclooxygenase 2 (COX-2), is deregulated i…

observational 2017
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117691142

Endometriosis is frequently associated with infertility and it is believed that the impairment of endometrial receptivity may be one of the mechanisms involved in this condition. Pinopodes are endometrial cycle-dependent structures that see…

observational 2016
Cell and tissue research ·doi:10.1007/s00441-016-2428-4

Impaired oocyte quality and oxidative stress might be involved in the pathogenesis of endometriosis-related infertility. To improve our understanding of the role of oxidative stress in this condition, we compare eight oxidative stress marke…

lab-animal 2015
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115602772

This study evaluated the potential protective effect of the antioxidants, l-carnitine (LC) and N-acetyl-cysteine (NAC), in preventing meiotic oocyte damage induced by follicular fluid (FF) from infertile women with mild endometriosis (ME). …

2013
Reprodução & Climatério ·doi:10.1016/j.recli.2013.08.001

Menores taxas de gestação em portadoras de endometriose submetidas a técnicas de reprodução assistida podem estar relacionadas à piora da qualidade oocitária. A análise da expressão gênica em células do cumulus (CC) pode fornecer biomarcado…