Seok Hyun Kim

BackgroundFemale infertility is a crucial problem with significant implications for individuals and society. In this study, we explore risk factors for infertility in Korean women.MethodsA total of 986 female patients who visited six major …

Research-questionWhat is the clinical usefulness of oocyte cryopreservation for fertility preservation in women with ovarian endometriosis?DesignClinical characteristics were retrospectively analysed in 34 women with endometrioma before a p…

This study aimed to analyze the effects of a new protocol with letrozole on the outcomes of in vitro fertilization (IVF) cycles in women with endometriosis. This retrospective cohort study was conducted for women diagnosed with endometriosi…

PurposeTo elucidate the correlation between ovarian reserve and the incidence of ectopic pregnancy (EP) following in vitro fertilization and embryo transfer (IVF/ET) cycles.Materials and methodsIn this observational study, 430 fresh IVF/ET …

PurposeTo investigate the associations between sperm DNA fragmentation (SDF) and embryo formation rate in normal responder women to in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI).Materials and methodsFifty-three consecut…

OBJECTIVE: This study aimed to determine whether the menstrual characteristics are different in Korean women with or without ovarian endometrioma. METHODS: We selected 95 premenopausal women aged below 39 years who underwent laparoscopic su…

OBJECTIVE: fertilization (IVF) outcomes between women with diminished ovarian reserve (DOR) after endometrioma operation and women with DOR without ovarian surgery. METHODS: This retrospective case-control study included 124 women aged unde…

This study aimed to investigate the potential detrimental effect of human endometriotic fluids (EFs) on in vitro growth of mouse preantral follicles. Preantral follicles (isolated from ovaries of 7- to 8-week-old mice) were cultured in grow…

Interleukin-2 receptor b gene C627T polymorphism in Korean women with endometriosis: a case–control study

OBJECTIVE: Elevated serum progesterone (P) levels on triggering day have been known to affect the pregnancy rate of in vitro fertilization (IVF). This study aimed to identify the possible factors influencing serum P levels on triggering day…

The aim of this study was to compare intrafollicular biomarkers of thiol-redox system and chronic inflammation in infertile patients with and without endometriosis, and examine correlations between biomarkers and IVF outcomes. The study inc…

This prospective study investigated the relationship between anti-Müllerian hormone (AMH) level in the follicular fluid (FF) and the quality of the oocyte and embryo. A total of 65 FF samples from 54 women were included in this study. FF wa…

OBJECTIVE: To evaluate the association between the severity of endometriosis and the preoperative neutrophil-to-lymphocyte ratio (NLR) and serum level of cancer antigen 125 (CA 125). METHODS: Data were obtained from the medical records of 4…

OBJECTIVE: To investigate the influence of laparoscopic surgery on the natural conception rate in infertile women with endometriosis during the first year after the operation. METHODS: We retrospectively studied 43 infertile women with surg…

PURPOSE: To investigate whether preoperative serum anti-mullerian hormone (AMH) levels are lower in women with ovarian endometrioma and in women with mature cystic teratoma of the ovaries. MATERIALS AND METHODS: In a tertiary university hos…

ObjectiveGenetic factors are known to be associated with the development and progression of endometriosis, but the genes related to endometriosis have not been defined. Insulin-like growth factor binding proteins (IGFBPs) are believed to be…

PurposeTo evaluate the relationship between endometriosis and polymorphisms in the genes encoding tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), TRAIL receptor (DR) and osteoprotegerin (OPG) and their serum levels in…

PROBLEM: To investigate the association between polymorphisms of the interleukin-1 (IL-1) family genes and endometriosis in Korean women. METHOD OF STUDY: In this case-control study, the IL-1α -889C>T, IL-1 receptor antagonist (IL-1RA) 86-b…

OBJECTIVES: To evaluate the relationship between endometriosis and polymorphisms in insulin-like growth factors (IGFs) and IGF-I receptor genes. STUDY DESIGN: In a case-control study, 128 women with endometriosis and 108 control women were…

PROBLEM: To investigate the association between endometriosis, transforming growth factor-β1 (TGFB1) gene polymorphisms, and serum TGF-β1 levels in Korean women. METHOD OF STUDY: The -509C/T, 868T/C, 913G/C and 979G/A polymorphisms of the T…

PROBLEM: To investigate whether the glutathione-S-transferase P1 (GSTP1) exon 5 polymorphism is associated with susceptibility to advanced stage endometriosis in Korean women. METHOD OF STUDY: Case-control study in a collective of 260 pati…

BACKGROUND: The purpose of this study was to investigate the potential association of the C627T polymorphism in the interleukin-2 receptor beta gene (IL-2R beta) with the risk of endometriosis in Korean women. METHODS: Two hundred and thirt…