Yutaka Osuga

No ORCID on file · 270 papers in corpus · active 1995-2026

Study types

  • article 198
  • other 29
  • review 13
  • preprint 10
  • book-chapter 7

Condition tags

  • endometriosis 201
  • adenomyosis 54
  • endometrioma 38
  • dysmenorrhea 28
  • infertility 24
  • chronic_pelvic_pain 11
  • dyspareunia 5
  • bowel_endometriosis 4
  • bladder_endometriosis 3
  • mesh:D004716 3
article 2023
Journal of perinatal medicine ·doi:10.1515/jpm-2023-0263

OBJECTIVES: Adenomyosis is associated with unfavorable perinatal outcomes, and recent case reports show that some women with adenomyosis experience pain at the adenomyosis lesion during pregnancy and have detrimental perinatal outcomes. Thi…

review 2023
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15759

Recurrent implantation failure (RIF) remains a challenging problem in assisted reproductive technology (ART). Further insights into uterine abnormalities that can disturb embryo implantation should be obtained. This review provides an overv…

article 2023
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians ·doi:10.1080/14767058.2023.2226789

OBJECTIVES: Although adenomyosis is reportedly associated with adverse pregnancy outcomes, clinical factors related to the high risk of obstetric complications are unclear. This study aimed to elucidate the characteristics of adenomyosis le…

preprint 2023
·doi:10.21203/rs.3.rs-2847062/v1

Abstract Ulipristal (UPA), a selective progesterone receptor modulator, has both agonistic and antagonistic effects on progesterone receptors. UPA suppresses ovulation by inhibiting the luteinizing hormone (LH) surge from the pituitary glan…

article 2023
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15849

AIM: We aimed to investigate the associations of endometriosis and adenomyosis with pregnancy complications by using a large-scale Japanese database. METHODS: We retrospectively analyzed 145 590 singleton pregnancies from the Japan Perinat…

other 2023
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-022-01077-9

Levonorgestrel-releasing intrauterine system (LNG-IUS) relieves dysmenorrhea and heavy menstrual bleeding (HMB) in adenomyosis. However, its efficacy on health-related quality of life (HR-QOL) in patients with symptomatic adenomyosis remain…

other 2023
AJOG global reports ·doi:10.1016/j.xagr.2023.100265

BACKGROUND: Adenomyosis is associated with unfavorable perinatal outcomes; however, the effect of an adenomyomectomy on pregnancy outcomes remains unclear. Pregnancy following an adenomyomectomy has been reported to be associated with a hig…

article 2023
BMC pregnancy and childbirth ·doi:10.1186/s12884-023-05956-0

BACKGROUND: Adenomyosis is a common gynecological disease in women of reproductive age and causes various symptoms such as dysmenorrhea and heavy menstrual bleeding. However, the influence of pregnancy on the progression of adenomyosis rema…

preprint 2023
·doi:10.21203/rs.3.rs-2834252/v1

Abstract Background Previous studies have shown the ovarian carcinoma after laparscopic cystectomy of endometrioma arises through the recurrence of endometrioma. Then it can be assumed that reduction of ovarian endometrioma recurrence throu…

book-chapter 2022
·doi:10.1007/978-3-030-97236-3_36
preprint 2022
·doi:10.22541/au.166746976.62381783/v1

Objective To clarify the clinical characteristics of pain developing in adenomyosis lesions during pregnancy and the perinatal outcomes associated with this phenomenon. Study Design Retrospective cohort study. Setting A tertiary hospital in…

article 2022
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15416

More than 10 years following the publication of "The General Rules for Clinical Management of Endometriosis: The second edition" in January 2010, the long-awaited third edition has arrived. The second edition represents the bible for endome…

article 2022
Endocrinology ·doi:10.1210/endocr/bqac044

Adenomyosis is a benign uterine disease that causes dysmenorrhea, heavy menstrual bleeding, and infertility; however, its pathophysiology remains unclear. Since signal transducer and activator of transcription 3 (STAT3) is crucial for endom…

article 2022
·doi:10.1016/j.jval.2022.04.494
review 2022
·doi:10.1007/s12325-022-02298-9

INTRODUCTION: Although several studies suggest beneficial effects of low-dose estrogen-progestins (LEPs) and progestins on dysmenorrhea in Japanese women, the difference in efficacy between drugs remains unknown. METHODS: We identified stud…

article 2022
F&S science ·doi:10.1016/j.xfss.2022.04.004

OBJECTIVE: To evaluate the phosphorylation of estrogen receptor α at serine-118 (phospho-ERα S118) in the endometrium, ovarian endometrioma, and deep infiltrating endometriosis (DIE). DESIGN: Experimental study. SETTING: University-affili…

article 2022
BMC women's health ·doi:10.1186/s12905-022-01917-5

BACKGROUND: Endometriosis is assumed to be involved in ovarian cancer development, which is called endometriosis-associated ovarian cancer (EAOC). Uterine endometrial cells may be the cell of origin of EAOC. Accumulated carcinogenic changes…

book-chapter 2022
·doi:10.1016/b978-0-323-90805-4.00004-3
preprint 2022
·doi:10.21203/rs.3.rs-1332354/v2
article 2022
Scientific reports ·doi:10.1038/s41598-022-22413-8

The purpose of this study was to establish a novel mouse model of adenomyosis suitable for longitudinal and quantitative analyses and perinatal outcome studies. Using a 30 G needle, the entire uterine wall of one horn was mechanically punct…

preprint 2022
·doi:10.21203/rs.3.rs-1332354/v1
article 2022

Aim: Endometriosis is linked to asymptomatic atherosclerosis and increases the risk of cardiovascular disease (CVD). Vascular function tests are used to assess atherosclerosis, an important indicator of CVD development. In this study, we ai…

article 2022
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15447

AIM: Endometriosis is linked to asymptomatic atherosclerosis and increases the risk of cardiovascular disease (CVD). Vascular function tests are used to assess atherosclerosis, an important indicator of CVD development. In this study, we ai…

article 2022
·doi:10.1016/j.xfnr.2022.11.004
other 2022
Biomedicines ·doi:10.3390/biomedicines10102627

The purpose of this study was to establish a new mouse model of endometriosis that mimics real-world women's health problems, in which women continue to be affected by endometriosis long before they wish to become pregnant, and to evaluate …