Eisenberg ML

Study questionTo what extent is male physical activity (PA) associated with fecundability (per-cycle probability of conception)?Summary answerPreconception levels of vigorous, moderate, or total PA were not consistently associated with fecu…

There is a natural balance between the major sex steroids, testosterone and estradiol, controlled by gonadal secretion and peripheral conversion by aromatase. This balance is impacted by a variety of inborn and acquired conditions, and, mor…

Study questionTo what extent do self-reported sleep duration and non-daytime work schedules in either partner affect the rate of spontaneous abortion (SAB)?Summary answerIncidence of SAB had little association with female sleep duration and…

Study questionTo what extent is preconception maternal or paternal coronavirus disease 2019 (COVID-19) vaccination associated with miscarriage incidence?Summary answerCOVID-19 vaccination in either partner at any time before conception is n…

ObjectiveTo describe the prevalence and treatment characteristics of assisted reproductive technology (ART) cycles involving specific male factor infertility diagnoses in the United States.DesignCross-sectional analysis of ART cycles in the…

Study questionIs there an association between fertility status, method of conception and the risks of birth defects and childhood cancer?Summary answerThe risk of childhood cancer had two independent components: (i) method of conception and…

Study questionIs fecundity, measured as self-reported time to first pregnancy (TTP), a marker for subsequent health and survival?Summary answerLong TTP was a marker for increased mortality among women and higher hospitalization rates for bo…

PurposeExcess embryos transferred (ET) (> plurality at birth) and fetal heartbeats (FHB) at 6 weeks' gestation are associated with reductions in birthweight and gestation, but prior studies have been limited by small sample sizes and limite…

BackgroundInfertility affects 15%-25% of all couples during their reproductive life span. It is a significant societal and public health problem with potential psychological, social, and economic consequences. Furthermore, infertility has b…

Study questionWhat is the association between ART conception and treatment parameters and the risk of birth defects?Summary answerCompared to naturally conceived singleton infants, the risk of a major nonchromosomal defect among ART singlet…

Study questionHas there been there a temporal change in time-to-pregnancy (TTP) in the USA.Summary answerOverall, TTP was stable over time, but a longer TTP for women over 30 and parous women was identified.What is known alreadyFertility ra…

PurposeOngoing evidence has suggested the role of male factor infertility as a potential predictor of mortality and general health status. The aim of the present review is to update the current knowledge base regarding the association betwe…

BackgroundAlthough in vitro fertilization has been associated with an increased risk for hypertensive disorders of pregnancy, the association of risk with in vitro fertilization treatment parameters is unclear.ObjectiveTo evaluate risk for …

STUDY QUESTION: Is female infertility associated with higher risk of cancer? SUMMARY ANSWER: Although absolute risks are low, infertility is associated with higher risk of cancer compared to a group of non-infertile women. WHAT IS KNOWN A…

Study questionDoes the fertility status of an individual act as a biomarker for their future health?Summary answerData support an association between reproductive health and overall health for men and women.What is already knownVarious chro…

We studied a prospective cohort of 434 couples in Northern California and found that 13% did not pursue any form of infertility treatment after their initial consultation. Although age, education, and financial concerns remain important for…