F&S reports

F S Rep · ISSN (e) 2666-3341 · 143 papers in corpus
case-report 2026
doi:10.1016/j.xfre.2026.04.012 ·PMID:42630765

OBJECTIVE: To describe a novel surgical approach for the detection and excision of peritoneal endometriosis using intraoperative Aqua Blue Contrast (ABC) with real-time AI-assisted detection. DESIGN: Case report describing a novel intraope…

other 2026
doi:10.1016/j.xfre.2025.11.005 ·PMID:41694261

OBJECTIVE: To study the associations of B cell lymphoma 6 (BCL6) in endometrial endometriosis, and to determine a practice's experience testing BCL6 in patients with recurrent pregnancy loss/recurrent implantation failure (RPL/RIF). DESIGN…

case-report 2026
doi:10.1016/j.xfre.2025.12.009 ·PMID:42027662

OBJECTIVE: To describe a case of severe infectious complications following ovarian platelet-rich plasma (PRP) injections for ovarian rejuvenation. DESIGN: Case report. SUBJECTS: A 45-year-old nulligravid woman with a history of uterine fi…

other 2026
doi:10.1016/j.xfre.2025.09.007 ·PMID:41694258
case-report 2026
doi:10.1016/j.xfre.2026.01.004 ·PMID:42027656

OBJECTIVE: To report the first live birth in Europe, and the fifth worldwide, after uterine and adnexal transposition (UT) for fertility preservation in rectal cancer, and to review all published neonatal outcomes after UT. DESIGN: Single-…

observational 2026
doi:10.1016/j.xfre.2025.12.006 ·PMID:41694264

OBJECTIVE: To evaluate the association between prior mode of delivery (cesarean vs. vaginal) and endometrial thickness in the subsequent frozen embryo transfer (FET) cycle. The secondary aim was to evaluate FET cycle outcomes. DESIGN: Retr…

rct 2026
doi:10.1016/j.xfre.2025.12.002 ·PMID:41694262

OBJECTIVE: To study the impact of estetrol (E4), a novel native estrogen with selective tissue activity, on endometriosis-associated pelvic pain (EAPP) and global impressions of endometriosis pain. DESIGN: Multicenter, randomized, open-lab…

rct 2026
doi:10.1016/j.xfre.2026.07.003 ·PMID:42903641

ObjectiveTo evaluate the efficacy, safety, and pharmacodynamics of linzagolix, an oral gonadotropin-releasing hormone (GnRH) receptor antagonist, in patients with heavy menstrual bleeding (HMB) and pain because of uterine fibroids.DesignPha…

rct 2026
doi:10.1016/j.xfre.2026.08.003 ·PMID:42903651

ObjectiveTo study whether microfluidic sperm separation in intracytoplasmic sperm injection cycles provides any benefit over density gradient sperm separation for good-quality embryo formation.DesignRandomized sibling oocyte study.SubjectsP…

2026
review 2026
doi:10.1016/j.xfre.2026.07.005 ·PMID:42903633

Dopamine D2 receptor (DRD2) agonists represent a promising targeted, nonhormonal therapeutic strategy for endometriosis. These agents selectively downregulate vascular endothelial growth factor-A signaling, thereby inhibiting the aberrant a…

other 2026
doi:10.1016/j.xfre.2026.08.006 ·PMID:42903392
case-report 2026
doi:10.1016/j.xfre.2026.04.006 ·PMID:42325714

OBJECTIVE: To report a case of polypoid ovarian endometrioma mimicking malignant transformation, review the literature on this rare entity, and highlight its implications for surgical management and fertility preservation. DESIGN: Case rep…

other 2026
doi:10.1016/j.xfre.2025.11.009 ·PMID:41694263
observational 2026
doi:10.1016/j.xfre.2026.02.007 ·PMID:42027659

OBJECTIVE: To study whether incident endometriosis diagnosis, staging, and typology are associated with concurrent elevated serum inflammatory markers interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF- α ). …

other 2026
doi:10.1016/j.xfre.2025.12.008 ·PMID:41694260
observational 2026
doi:10.1016/j.xfre.2025.12.003 ·PMID:41694253

OBJECTIVE: To study changes in the rate and potential causes of second-trimester loss (STL) after in vitro fertilization (IVF) after 2 decades marked by the gradual adoption of elective single embryo transfer. DESIGN: Retrospective cohort …

other 2026
doi:10.1016/j.xfre.2026.04.010 ·PMID:42325724

Few scenarios in gynecologic surgery test clinical judgment more than the evaluation of an adnexal mass suspicious for malignancy. Nowhere is this challenge more pronounced than in patients with endometriosis, a disease that is at once comm…

observational 2026
doi:10.1016/j.xfre.2026.06.008 ·PMID:42903621

ObjectiveTo investigate sociodemographic and clinical variables associated with Whole Systems Traditional Chinese Medicine (WS-TCM) utilization alongside frozen embryo transfers (FETs) after in vitro fertilization.DesignWe conducted a retro…

other 2025
doi:10.1016/j.xfre.2025.08.003 ·PMID:41054714
review 2025
doi:10.1016/j.xfre.2025.01.010 ·PMID:40487319

Animal models of human disease have been used for a long time, and frequently, diseases in these models are induced, rather than spontaneous. The present review outlines several examples of naturally occurring reproductive diseases in non-d…

observational 2025
doi:10.1016/j.xfre.2024.12.001 ·PMID:40201096

OBJECTIVE: To determine whether follicle size at midcycle transvaginal sonography imaging before luteal progesterone supplementation predicts modified natural cycle single frozen embryo transfer (mNC-SFET) outcomes. DESIGN: Retrospective c…

rct 2025
doi:10.1016/j.xfre.2025.07.003 ·PMID:41054720

OBJECTIVE: To evaluate the risk of ovarian hyperstimulation syndrome (OHSS) with highly purified human menopausal gonadotropin (HP-hMG) or recombinant follicle-stimulating hormone (rFSH) for controlled ovarian stimulation in patients predic…

observational 2025
doi:10.1016/j.xfre.2025.02.008 ·PMID:40620374

OBJECTIVE: To study the impact of maternal race and ethnicity on live birth rates (LBRs) in white, Asian, Hispanic, and African American women with infertility, with and without polycystic ovary syndrome (PCOS), undergoing in vitro fertiliz…

other 2025
doi:10.1016/j.xfre.2025.05.001 ·PMID:40620365