F&S reports

OBJECTIVE: To evaluate the safety and pharmacokinetics/pharmacodynamics of AMY109, an anti-interleukin-8 recycling antibody in a first-in-human phase 1 trial in healthy volunteers (HVs) and patients with endometriosis. DESIGN: A multicente…

ObjectiveTo study the earliest timepoint at which serum human chorionic gonadotropin (hCG) can predict live birth after blastocyst frozen embryo transfer, and to determine the cutoff values for hCG levels on days 7-11 after frozen-thawed em…

ObjectiveTo describe conservative management for accessory and cavitated uterine mass (ACUM) with norethindrone acetate. The patient gave signed written, informed consent authorizing publication.DesignWe present a case report of a patient w…

ObjectiveTo investigate the time to pregnancy in women ≤37 years of age with high response to controlled ovarian stimulation and undergoing an initial fresh transfer vs. those women proceeding with a freeze-all strategy.DesignA retrospectiv…

ObjectiveTo compare clinical outcomes between nonindicated intracytoplasmic sperm injection (ICSI) and conventional insemination.DesignAutologous cycles performed from 2014-2017 were identified, excluding frozen oocyte cycles. Outcomes were…

ObjectiveTo compare neonatal outcomes in pregnancies resulting from embryos that have undergone preimplantation genetic testing (PGT) biopsy compared with no biopsy in both fresh and frozen embryo transfers (ETs) and determine whether findi…

ObjectiveTo compare ribonucleic acid (RNA) quantity and purity in tissue collected with different endometrial sampling methods to establish the optimal tool for use in endometrial gene expression studies.DesignObservational study.SettingUni…

OBJECTIVE: To investigate the prevalence of decisional regret regarding preoperative fertility preservation choices after gender-affirming surgery or removal of reproductive organs. DESIGN: Cross-sectional. SETTING: University-based prati…

ObjectiveTo compare women with proximal tubal obstruction (PTO) undergoing hysteroscopic tubal cannulation with fluoroscopic guidance vs. laparoscopic guidance.DesignRetrospective cohort study.SettingAll fluoroscopically-guided hysteroscopi…

ObjectiveTo compare pregnancy outcomes after single blastocyst embryo transfer among patients whose first autologous embryo transfer was either a fresh embryo transfer or a frozen embryo transfer (FET) after a freeze-all, in the absence of …

ObjectiveTo study the clinical and neonatal outcomes of embryos derived from frozen oocytes relative to fresh oocytes in both autologous and donor oocyte cycles after fresh embryo transfer (ET).DesignThis is a retrospective cohort study usi…

ObjectiveTo investigate the efficacy of elagolix plus add-back therapy (estradiol [1 mg] and norethindrone acetate [0.5 mg] once daily) on patient-reported nonbleeding symptoms and menstrual bleeding associated with uterine fibroids (UFs) a…

ObjectiveTo compare cumulative live birth rate (CLBR) and cost-effectiveness of intracytoplasmic sperm injection (ICSI) vs. conventional in vitro fertilization (cIVF).DesignRetrospective cohort study of cycles reported to the Society for As…

OBJECTIVE: To determine whether endometriosis typology, namely ovarian endometriomas (OE), deep infiltrating endometriosis (DIE), or superficial endometriosis (SE), correlates with fertility history. DESIGN: Prospective cohort. SETTING: O…

ObjectiveTo present the comprehensive methodology for generating personalized three-dimensional (3D) printed uterine models from 3D ultrasound (US) volumes in individuals diagnosed with Müllerian anomalies and discuss potential applications…

ObjectiveTo study the impact of polycystic ovary syndrome (PCOS) on work-related impairments and explore relationships with race, mental health, and healthcare delivery indices.DesignA cross-sectional internet-based survey.SettingNorth Amer…

Programmed or medicated frozen embryo transfer cycles rely on exogenous progesterone (P) administration to prepare the endometrium for implantation and maintain pregnancy. Presently, the optimal route and dose of P replacement for frozen em…

ObjectiveTo describe differences in the frequency of small-for-gestational age (SGA) and large-for-gestational age (LGA) driven by different birth weight curves in assisted reproductive technology (ART)-conceived pregnancies.DesignRetrospec…

Objective: To compare in vitro fertilization treatment outcomes for the oral gonadotropin-releasing hormone (GnRH) antagonist elagolix (E) to the conventionally used injectable GnRH antagonist ganirelix (G) for achieving pituitary gonadotro…