F&S reports

OBJECTIVE: To evaluate the safety and pharmacokinetics/pharmacodynamics of AMY109, an anti-interleukin-8 recycling antibody in a first-in-human phase 1 trial in healthy volunteers (HVs) and patients with endometriosis. DESIGN: A multicente…

OBJECTIVE: To study the earliest timepoint at which serum human chorionic gonadotropin (hCG) can predict live birth after blastocyst frozen embryo transfer, and to determine the cutoff values for hCG levels on days 7-11 after frozen-thawed …

OBJECTIVE: To describe conservative management for accessory and cavitated uterine mass (ACUM) with norethindrone acetate. The patient gave signed written, informed consent authorizing publication. DESIGN: We present a case report of a pat…

OBJECTIVE: To investigate the time to pregnancy in women ≤37 years of age with high response to controlled ovarian stimulation and undergoing an initial fresh transfer vs. those women proceeding with a freeze-all strategy. DESIGN: A retros…

OBJECTIVE: To compare clinical outcomes between nonindicated intracytoplasmic sperm injection (ICSI) and conventional insemination. DESIGN: Autologous cycles performed from 2014-2017 were identified, excluding frozen oocyte cycles. Outcome…

OBJECTIVE: To compare neonatal outcomes in pregnancies resulting from embryos that have undergone preimplantation genetic testing (PGT) biopsy compared with no biopsy in both fresh and frozen embryo transfers (ETs) and determine whether fin…

OBJECTIVE: To compare ribonucleic acid (RNA) quantity and purity in tissue collected with different endometrial sampling methods to establish the optimal tool for use in endometrial gene expression studies. DESIGN: Observational study. SE…

OBJECTIVE: To investigate the prevalence of decisional regret regarding preoperative fertility preservation choices after gender-affirming surgery or removal of reproductive organs. DESIGN: Cross-sectional. SETTING: University-based prati…

OBJECTIVE: To compare women with proximal tubal obstruction (PTO) undergoing hysteroscopic tubal cannulation with fluoroscopic guidance vs. laparoscopic guidance. DESIGN: Retrospective cohort study. SETTING: All fluoroscopically-guided hy…

OBJECTIVE: To compare pregnancy outcomes after single blastocyst embryo transfer among patients whose first autologous embryo transfer was either a fresh embryo transfer or a frozen embryo transfer (FET) after a freeze-all, in the absence o…

OBJECTIVE: To study the clinical and neonatal outcomes of embryos derived from frozen oocytes relative to fresh oocytes in both autologous and donor oocyte cycles after fresh embryo transfer (ET). DESIGN: This is a retrospective cohort stu…

OBJECTIVE: To investigate the efficacy of elagolix plus add-back therapy (estradiol [1 mg] and norethindrone acetate [0.5 mg] once daily) on patient-reported nonbleeding symptoms and menstrual bleeding associated with uterine fibroids (UFs)…

OBJECTIVE: To compare cumulative live birth rate (CLBR) and cost-effectiveness of intracytoplasmic sperm injection (ICSI) vs. conventional in vitro fertilization (cIVF). DESIGN: Retrospective cohort study of cycles reported to the Society …

OBJECTIVE: To determine whether endometriosis typology, namely ovarian endometriomas (OE), deep infiltrating endometriosis (DIE), or superficial endometriosis (SE), correlates with fertility history. DESIGN: Prospective cohort. SETTING: O…

OBJECTIVE: To present the comprehensive methodology for generating personalized three-dimensional (3D) printed uterine models from 3D ultrasound (US) volumes in individuals diagnosed with Müllerian anomalies and discuss potential applicatio…

OBJECTIVE: To study the impact of polycystic ovary syndrome (PCOS) on work-related impairments and explore relationships with race, mental health, and healthcare delivery indices. DESIGN: A cross-sectional internet-based survey. SETTING: …

Programmed or medicated frozen embryo transfer cycles rely on exogenous progesterone (P) administration to prepare the endometrium for implantation and maintain pregnancy. Presently, the optimal route and dose of P replacement for frozen em…

OBJECTIVE: To describe differences in the frequency of small-for-gestational age (SGA) and large-for-gestational age (LGA) driven by different birth weight curves in assisted reproductive technology (ART)-conceived pregnancies. DESIGN: Ret…

The incorrect conclusion about vaginally administered progesterone: when a randomized clinical trial gets it wrong