The importance of quantifying the adverse effects on healthcare-related quality of life in people with benign gynecologic conditions

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This paper argues for the critical importance of quantifying adverse effects on healthcare-related quality of life within the context of benign gynecologic conditions. The authors highlight that while treatment efficacy is often measured by clinical outcomes, patient-reported experiences regarding quality of life are equally vital for comprehensive care assessment. By emphasizing this metric, the study advocates for a more holistic approach to evaluating therapeutic interventions in gynecology. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Credit

Elizabeth L. Wolfe: Writing – original draft. LaTasha B. Craig: Writing – review & editing.

Coi Statement

E.L.W. has nothing to disclose. L.B.C. reports funding from Oklahoma Shared Clinical and Translational Resource Institute NIGMS U54GM104938, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH/NICHD, Presbyterian Health Foundation, OU College of Medicine Alumni Association; honoraria and travel support from Ferring Pharmaceuticals; planned and pending patent: methods and compositions for treating diseases and conditions associated with gonadotropin-releasing hormone receptor." (Application: February 23, 2018); and a leadership role in the American Board of Obstetrics and Gynecology division of Reproductive Endocrinology & Infertility.

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europepmc
last seen: 2026-10-04T09:26:46.659050+00:00
pubmed
last seen: 2026-10-08T21:44:52.281569+00:00
unpaywall
last seen: 2026-09-10T06:36:06.991349+00:00
License: CC-BY-NC-ND-4.0