When benign mimics malignancy: a call for surgical restraint and clinical nuance in endometriosis-associated ovarian masses
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This paper discusses endometriosis-associated ovarian masses that can resemble malignancy, urging for surgical restraint and nuanced clinical evaluation to avoid unnecessary interventions.
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Abstract
Few scenarios in gynecologic surgery test clinical judgment more than the evaluation of an adnexal mass suspicious for malignancy. Nowhere is this challenge more pronounced than in patients with endometriosis, a disease that is at once common, heterogeneous, and biologically complex. Affecting approximately 10% of reproductive-age women, endometriosis frequently involves the ovary in the form of endometriomas (1). Although overwhelmingly benign, these lesions exist within a spectrum that includes a small but real risk of malignant transformation, most notably into endometrioid and clear cell carcinomas.
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References (4)
- Four ovarian cancers diagnosed during laparoscopic management of 1011 women with adnexal masses via openalex
- New insights in the pathophysiology of ovarian cancer and implications for screening and prevention via openalex
- The relationship of endometriosis and ovarian malignancy: a review via openalex
- W2989369163 via openalex
Source provenance
- europepmc
- last seen: 2026-07-30T06:25:42.655704+00:00
- openalex
- last seen: 2026-07-30T06:08:59.260406+00:00
- pubmed
- last seen: 2026-07-30T06:11:56.149277+00:00
License: CC0
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