Shizuka Mita

ORCID: 0000-0001-7626-1862 · 12 papers in corpus · active 2007-2021

Study types

  • article 11
  • other 1

Condition tags

  • mesh:D004715 6
  • endometriosis 4
  • endometrioma 1
article 2021
Identification of biomarkers for drug-resistant endometriosis using clinical proteomics
Human cell ·doi:10.1007/s13577-020-00465-0
article 2018
Dienogest suppresses the activation of primordial follicles and preserves the primordial follicle stockpile for fertility in mice
·doi:10.1016/j.rbmo.2017.12.018
other 2017
Dienogest inhibits C-C motif chemokine ligand 20 expression in human endometriotic epithelial cells
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2017.04.048

OBJECTIVE: C-C motif chemokine ligand 20 is thought to contribute to the development of endometriosis by recruiting Th17 lymphocytes into endometriotic foci. The present study investigated the effects of dienogest, a progesterone receptor a…

article 2016
Endometriotic cyst fluid induces reactive oxygen species (ROS) in human immortalized epithelial cells derived from ovarian endometrioma
Redox report : communications in free radical research ·doi:10.1080/13510002.2016.1258448

OBJECTIVES: Endometriotic cyst fluid (ECF) contains a large amount of reactive oxygen species (ROS), and endometriotic cysts are exposed to strong oxidative stress, which may cause malignant transformation. In this study, ROS production by …

article 2014
Dienogest, a synthetic progestin, down-regulates expression of CYP19A1 and inflammatory and neuroangiogenesis factors through progesterone receptor isoforms A and B in endometriotic cells
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2014.12.008
article 2014
Dienogest improves human leucocyte antigen-DR underexpression and reduces tumour necrosis factor-α production in peritoneal fluid cells from women with endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2014.03.019
article 2013
Dienogest inhibits nerve growth factor expression induced by tumor necrosis factor-α or interleukin-1β
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.10.038
article 2012
Dienogest inhibits aromatase and cyclooxygenase-2 expression and prostaglandin E2 production in human endometriotic stromal cells in spheroid culture
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.11.005
article 2011
Dienogest inhibits Toll-like receptor 4 expression induced by costimulation of lipopolysaccharide and high-mobility group box 1 in endometrial epithelial cells
·doi:10.1016/j.fertnstert.2011.09.040
article 2010
Dienogest, a synthetic progestin, inhibits prostaglandin E2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system
Steroids ·doi:10.1016/j.steroids.2010.08.010
article 2009
Dienogest, a synthetic progestin, inhibits the proliferation of immortalized human endometrial epithelial cells with suppression of cyclin D1 gene expression
Molecular human reproduction ·doi:10.1093/molehr/gap042

Dienogest is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis. In this study, we examined the direct effects of dienogest on the proliferation of human endometrial …

article 2007
Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile
·doi:10.1016/j.steroids.2007.10.003