Hao Lin

No ORCID on file · 13 papers in corpus · active 2003-2025

Study types

  • article 6
  • other 4

Condition tags

  • endometriosis 6
  • adenomyosis 4
  • infertility 3
  • dysmenorrhea 2
  • endometrioma 1
other 2025
Exploring Salvia miltiorrhiza's Therapeutic Effects on Adenomyosis by Inhibiting TNF-α/HIF-1α/IL-17-Driven Inflammatory Cascade: Mechanistic Insights from Target Prediction and Experimental Validation
Journal of inflammation research ·doi:10.2147/JIR.S537221

BACKGROUND: Adenomyosis is a chronic inflammatory gynecological disorder closely linked with diminished fertility potential that poses significant challenges in pharmacological management. Salvia miltiorrhiza (Danshen, DS), a traditional Ch…

article 2025
Identification of novel causally related genes in adenomyosis: An integrated summary data-based Mendelian randomization study and bioinformatics analysis
Medicine ·doi:10.1097/md.0000000000042768

Adenomyosis (AM) is recognized as a complex gynecological and endocrine disorder that contributes to infertility and elevates the risk of pregnancy complications; however, its underlying genetic basis remains unidentified. This study aimed …

other 2025
Integrated multi-omics analysis and experimental verification reveal the involvement of the PI3K/Akt signaling pathway in myometrial fibrosis of adenomyosis
Scientific reports ·doi:10.1038/s41598-025-98369-2

Adenomyosis (AM) is characterized as a chronic and progressive disorder with limited therapeutic strategies available. Myometrial fibrosis is a prominent pathological feature of AM, yet the underlying molecular mechanisms remain elusive. Th…

2025
Molecular Interplay Between PTEN, ARID1A, PD-L1, and MMR in Asian Ovarian Clear Cell Carcinoma: Implications for Immunotherapy Response and Patient Stratification.
International journal of molecular sciences ·doi:10.3390/ijms26104915

Ovarian clear cell carcinoma (OCCC) represents a distinct histological subtype with a high prevalence in Asian populations and poor chemotherapy response. This study investigated molecular interactions between phosphatase and tensin homolog…

article 2025
Uterine artery S/D ratio and serum CA125 as predictors of early pregnancy loss in women with ovarian endometriomas: a retrospective case-control study
BMC pregnancy and childbirth ·doi:10.1186/s12884-025-08513-z

BACKGROUND: Endometriosis affects approximately 10% of women of reproductive age and is associated with increased risks of infertility and miscarriage. Although the spontaneous miscarriage rate in women with endometriosis is higher than in …

other 2025
Uterine transverse diameter and risk of LNG-IUS malposition in adenomyosis patients: a threshold effect analysis from a retrospective cohort study
BMC women's health ·doi:10.1186/s12905-025-03997-5

OBJECTIVE: The malposition of the levonorgestrel-releasing intrauterine system (LNG-IUS) can have a considerable impact on the treatment outcomes for patients with adenomyosis. This study was designed to explore the relationship between the…

2022
Endometrial Cancer Detection Using a Cervical DNA Methylation Assay (MPap) in Women with Abnormal Uterine Bleeding: A Multicenter Hospital-Based Validation Study.
Cancers ·doi:10.3390/cancers14174343

BackgroundWe describe a DNA methylation assay, named MPap test, using cervical scraping as an alternative technique for endometrial cancer detection.MethodsA multicenter hospital-based, two-stage validation study was conducted to validate t…

other 2022
Predicting Long-Term Prognoses and Grading Platinum Sensitivity Using a Novel Progression-Free Interval Criterion in Ovarian Clear Cell Carcinoma: A Multi-Institutional Cohort Study
Cancers ·doi:10.3390/cancers14071746

This large-scale study aimed to determine the long-term influences of potential prognostic predictors and progression-free interval (PFI) criteria for grading platinum-sensitivity in ovarian clear cell carcinoma (OCCC). We retrospectively r…

2017
Malignant transformation of ovarian mature cystic teratoma into squamous cell carcinoma: a Taiwanese Gynecologic Oncology Group (TGOG) study.
Journal of gynecologic oncology ·doi:10.3802/jgo.2017.28.e69

ObjectiveThe malignant transformation (MT) of ovarian mature cystic teratoma (MCT) to squamous cell carcinoma (SCC) is very rare. This study analyzed cases from multiple medical centers in Taiwan to investigate the clinicopathologic charact…

article 2011
A Possible Mechanism of Autoimmune‐Mediated infertility in Women with Endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2010.00956.x

PROBLEM: Endometriosis has been proposed to be an autoimmune disease because of the presence of a variety of autoantibodies specific for endometrial or ovarian antigens. The object of the present study is to characterize binding specificity…

article 2005
Extrauterine mullerian adenosarcoma associated with endometriosis and rectal villotubular adenoma: report of a case and review of the literature
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1111/j.1525-1438.2005.15230.x

Extrauterine mullerian adenosarcoma is rare and is thought to arise from endometriotic deposits or pluripotent mesothelial and mesenchymal cells of the pelvic cavity. Concomitant colon-rectal neoplasm was reported but the relationship betwe…

article 2005
Extrauterine müllerian adenosarcoma associated with endometriosis and rectal villotubular adenoma: report of a case and review of the literature
·doi:10.1136/ijgc-00009577-200503000-00029
article 2003
Small Intestine Injury in Laparoscopic-Assisted Vaginal Hysterectomy
The Journal of the American Association of Gynecologic Laparoscopists ·doi:10.1016/s1074-3804(05)60260-5

Study objectiveTo review laparoscopic-assisted vaginal hysterectomy (LAVH) cases for instances of small intestine injury.DesignRetrospective review (Canadian Task Force Classification II-2).SettingTertiary care university hospital.PatientsT…