Yali Li

BACKGROUND: Endometriosis (EMs) is a common gynecological disorder characterized by endometrial-like tissue outside the uterus. Hypoxia induces the expression of many important downstream genes to regulate the implantation, survival, and ma…

OBJECTIVE: To determine the effects of hypobaric hypoxia pretreatment on surgically induced endometriosis in rats. METHODS: ) for 8 h. The uterine endometrium was intraperitoneally implanted into estrogen-treated ovariectomized Lewis rat, a…

OBJECTIVE: This study measured the human epididymis protein 4 (HE4) and CA125 levels in Chinese women with benign gynecological disorders. MATERIAL AND METHODS: Sera were obtained from Chinese women prior to surgery for a pelvic mass and HE…

OBJECTIVE: To evaluate the effects of lesion location on adhesion and angiogenesis of transplanted endometriotic lesions in SCID mice. METHODS: Three groups of female SCID mice included intraperitoneal (i.p.) (n = 12), subcutaneous (s.c.) …

OBJECTIVE: To investigate the effects of oxygen on the proliferation and angiogenesis of endometriosis in vivo. DESIGN: Animal studies. SETTING: Animal research facility. ANIMAL(S): Thirty-six female severe combined immunodeficiency (SCI…

Endometriosis is a complex and enigmatic disease that arises from the interplay among multiple genetic and environmental factors. The defining feature of endometriosis is the deposition and growth of endometrial tissues at sites outside of …

Rhodiola can enhance nonspecific immune system function,which is considered as adaptogen due to its multiple functions such as anti-hypoxic and estrogen-like properties.This review demonstrates the pharmacological mechanisms of Rhodiola whi…

OBJECTIVE: To determine the effects of carbon dioxide (CO(2)) and nitrogen (N(2)) pneumoperitoneums on endometriosis (EMs) lesions. METHODS: Female Wistar rats were randomized into the following 3 groups: CO(2) (N = 20), N(2) (N = 22) and a…

OBJECTIVE: To investigate the expression of the anti-oncogene ARHI in the endometriotic tissue and explore its clinical significance. METHODS: A semiquantitative analysis of the expression of ARHI mRNA and protein in the ectopic and eutopic…

Objective To analyze the effect of laparoscopic excision on deep infiltrating type endometriosis(DIE) in posterior pelvis.Methods Data of 35 cases of posterior pelvic DIE admitted to General Hospital of PLA from Jan.2006 to Jan.2009 were re…

OBJECTIVE: To establish a diagnostic model of endometriosis by analyzing serum peptidome patterns in patients with endometriosis using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS). METHODS: Ser…

Objective To study the application of hysteroscopy combined with laparoscopy in operation of patients with gynecological diseases and its indications.Methods Data about 236 patients who underwent operation by hysteroscopy combined with lapa…

Objective To set up an experimental endometriosis model using ER-β knockout mice,and to investigate the role of ER-β in the pathogenesis of endometriosis.Methods Autotransplantation of uterine tissue to ectopic sites in the abdominal wall w…

Objective To investigate the expression of gonadotropin-releasing hormone (GnRH) and its receptor (GnRH-R) in human endometriosis (EMS) and normal endometrial cells cultured in vitro. Methods Fresh eutopic endometrial specimens were collect…

OBJECTIVE: To investigate the distribution of ER isoforms in endometriosis and eutopic endometrium. METHODS: Tissue samples of patients with ovarian endometriosis, treated in People's Liberation Army General Hospital from January 2004 to De…

BACKGROUND: Direct and indirect evidences have suggested that angiogenesis is a prerequisite for the development of endometriosis. Aiming at offering experimental evidences for anti-angiogenesis therapy, we transplanted the eutopic endometr…

Objective:To find out the diagnostic value of ultrasonography to endometriosis.Methods:To retrospectively analyse the results of ultrasonography of 90 cases who were finally diagnosed by laparoscopy before operation.And compare ultrasonogra…

Objective:To detect the expression of vascular endothelial growth factor receptors(VEGFR)flt-1 and KDR mRNA in the ectopic and eutopic endometrium of patients with endometriosis.Methods:44 specimens of ovarian endometrioma and 30 eutopic en…

OBJECTIVE: To explore the potential use of integrin av beta3 (Lm609) monoclonal antibody against ectopic lesion and microvessel angiogenesis of human endometriosis xenografts in SCID mice. METHODS: The endometrial tissues from endometriosis…

O bjective To study the relationship between ascite s and endometriosis.Methods To compare 80 cases of endometri osi s with 50 cases of ascites without endometriosis, analyze the difference between them. Result Among the 80 cases with en do…

OBJECTIVE: To study the role of hepatocyte growth factor (HGF) and its receptor (c-Met) in the pathogenesis of endometriosis. METHODS: In situ hybridization and immunohistochemistry method was used to examine HGF mRNA and protein expression…

Scatter factor (hepatocyte growth factor, SF/HGF) is a multifunctional polypeptide growth factor that plays an important role in tumor proliferation, angiogenesis and invasiveness. The aim of this study was to investigate the role of HGF in…