Tommaso Falcone

The management of endometriosis and its impact on fertility is a complex and multifaceted challenge that requires a comprehensive understanding of the disease process, its relationship with fertility, and the available treatment options. Al…

OBJECTIVE: To assess the associations of time to endometriosis diagnosis after presentation for pelvic pain between patients of different ages, races, ethnicities, and body mass index (BMI) ranges. METHODS: This retrospective study was cond…

INTRODUCTION: Endometriosis is a chronic inflammatory condition affecting ~10% of reproductive-age individuals and contributing significantly to infertility, pain, and reduced quality of life. Since our 2020 review, new pharmacologic strate…

This group was formed out of the conviction that endometriosis research has not progressed at a pace in proportion to disease severity and the negative impact on women's quality of life. Furthermore, advancement in our understanding of this…

Adenomyosis is a benign gynecologic disorder that had previously not been well studied or understood. However, it is now become a more common diagnosis with long-standing implications especially for fertility. In this literature review, the…

Endometriosis is a common disease among women of reproductive age in which endometrial tissue grows in ectopic localizations, primarily within the pelvic cavity. These ectopic "lesions" grow as well as migrate and invade underlying tissues.…

Several mechanisms have been implicated in the pathogenesis of endometriosis-related infertility. For patients considering surgery, the risk of iatrogenic injury is among the most important factors in the context of fertility preservation, …

OBJECTIVE: To evaluate the perioperative outcomes of premenopausal women undergoing cystectomy or oophorectomy for ovarian endometriomas (OMAs) and other benign neoplasms. DESIGN: Retrospective cohort study. SETTING: Clinical database con…

Background: miR-451a can function as a tumor suppresser and has been shown to be elevated in both endometriotic lesion tissue and serum from women with endometriosis. To further explore the role of miR-451a in the pathophysiology of endomet…

Background: Chronic pelvic pain (CPP) has a significant impact on patients’ health-related quality of life (HRQoL). Endometriosis is a common cause of CPP. Data is lacking on long-term HRQoL outcomes in patients with endometriosis-associate…