T Mori

The aim of this study is to investigate cancer survival parameters in patients with a combination of adenomyosis and endometrial carcinoma in pathological specimens. This is a retrospective cohort study conducted in a tertiary health center…

The inhibitory effects of a novel, orally active matrix metalloproteinase (MMP) inhibitor, ONO-4817, on the development of uterine adenomyosis induced experimentally by pituitary grafting were examined in mice. Mice were given transplants o…

Prolactin receptor (PRLR) mRNA was visualized by in situ hybridization in adenomyotic uteri of mice with ectopic pituitary grafting. The signals of PRLR mRNA were mainly detected in the smooth muscle cells of myometrium and the epithelial c…

Adenomyosis is a benign pathologic disorder of the uterine endometrial tissues whereby endometrial components, such as glands and stroma, invade the myometrium. Transplantation of a single anterior pituitary gland into the uterine lumen ind…

OBJECTIVE: Our purpose was to investigate Bcl-2 and Fas expression in human eutopic and ectopic endometrium during the menstrual cycle in relation to endometrial cell apoptosis. STUDY DESIGN: Eutopic and ectopic endometrial samples were ob…

Although combined hormone replacement therapy using estrogens and progestins reduces the risk of endometrial cancer in postmenopausal women, it has been unclear whether the combined therapy is associated with an alteration of the risk of ma…

PROBLEM: To determine whether infertile patients with endometriosis have serum antiendometrial antibodies. METHODS: Sera from 40 infertile patients with or without endometriosis were tested by cell enzyme-linked immunosorbent assay (ELISA),…

The patterns of serum FSH, LH, PRL and GH levels in SHN mice were determined by radioimmunoassay between 1 and 12 months of age. In addition, the incidence of spontaneous development of uterine adenomyosis and mammary tumor was also studied…

The effects of traditional Chinese herbal remedies, Shakuyaku-kanzo-to (SKT) and Hachimijiou-gan (HJG), on the spontaneous development of uterine adenomyosis and mammary hyperplastic alveolar nodules (HAN) were examined in an experimental a…

Keishi-bukuryo-gan (KBG) is a traditional Chinese herbal remedy and has been used for the treatment of gynecological disorders, such as hypermenorrhea, dysmenorrhea, and infertility. The effects of KBG on the development of uterine adenomyo…

Abstract A total of 206 nongravid patients with various gynecologic problems underwent pelvic magnetic resonance (MR) examinations that included both sagittal T2‐weighted and contrast agent–enhanced T1‐weighted images. MR images were retros…

Indirect immunofluorescence staining revealed that endometrial stromal cells (ESC) in the ectopic endometrium of patients with endometriosis or adenomyosis expressed aminopeptidase N/cluster of differentiation (CD) 13 antigen and neutral en…

To evaluate further the chemopreventive role of motherwort (Leonurus sibiricus L; MW) in lesions of the mammary gland and uterus of GR/A mice, the effects on these lesions of the adsorbed (MW1) and unadsorbed (MW2) fractions of MW separated…

The immunohistochemical localization of the androgen receptor in the human endometrium at various stages of the menstrual cycle and post-menopausal period, in decidua and placenta of early pregnancy, and in several pathological conditions o…

Ectopic pituitary isografts (EPI) have been found to induce a high incidence of uterine adenomyosis in SHN mice. All the SHN mice given EPI in the right uterus at 40 days of age developed uterine adenomyosis, and more than 80% of mice showe…

Development of uterine adenomyosis was examined in BALB/c mice. Anterior pituitary (AP) isografting at 8 weeks of age significantly increased the incidence of adenomyosis in mice by 36 weeks of age as compared to that in control mice bearin…

The development and the progression of uterine adenomyosis were compared with those of mammary tumours in four strains of mice with different mammary tumour potentials. Cumulative mammary tumour incidences were the highest and the lowest in…