Lee DR

No ORCID on file · 5 papers in corpus · active 1996-2023

Study types

  • article 1

Condition tags

  • infertility 2
  • endometriosis 1
2023
RNA sequencing-based transcriptome analysis of granulosa cells from follicular fluid: Genes involved in embryo quality during in vitro fertilization and embryo transfer.
PloS one ·doi:10.1371/journal.pone.0280495

BackgroundGranulosa cells play an important role in folliculogenesis, however, the role of RNA transcripts of granulosa cells in assessing embryo quality remains unclear. Therefore, we aims to investigate that RNA transcripts of granulosa c…

2016
Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice.
Scientific reports ·doi:10.1038/srep20242

DGCR8 is an RNA-binding protein that interacts with DROSHA to produce pre-microRNA in the nucleus, while DICER generates not only mature microRNA, but also endogenous small interfering RNAs in the cytoplasm. Here, we produced Dgcr8 conditio…

2012
Chronic diseases in captive geriatric female Chimpanzees (Pan troglodytes).
Comparative medicine

The current aging population of captive chimpanzees is expected to develop age-related diseases and present new challenges to providing their veterinary care. Spontaneous heart disease and sudden cardiac death are the main causes of death i…

2006
Heparin-binding epidermal growth factor (HB-EGF) may improve embryonic development and implantation by increasing vitronectin receptor (integrin alphanubeta3) expression in peri-implantation mouse embryos.
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-006-9021-9

PurposeThis study investigated the effects of HB-EGF on expression of integrin alphanubeta3 and implantation of embryos.MethodsTwo-cell embryos were recovered and cultured with or without 10 ng/mL HB-EGF for 96h. Expression of integrin alph…

article 1996
Identification of rhesus macaques with spontaneous endometriosis
Journal of medical primatology ·doi:10.1111/j.1600-0684.1996.tb00027.x

Rhesus macaques (Macaca mulatta) with endometriosis were identified using reproductive histories, serum levels CA-125, pelvic ultrasonography, laparoscopy, and histopathology. All animals were evaluated from a large breeding colony and had …