Journal of medical primatology

Intravascular adenomyosis was discovered in a cynomolgus macaque, a previously unreported presentation of adenomyosis in non-human primates that points to vascular involvement in adenomyosis etiology. Uterus gross exam was unremarkable, but…

BACKGROUND: Endometriosis is the presence of endometrium-like tissue outside the uterine cavity. An experimental model of endometriosis has been created in the baboon by the transcervical collection and laparoscopic inoculation of menstrual…

Spontaneous endometriosis is common in women, great apes and Old World monkeys, but rare in New World monkeys. We report on the clinical diagnosis and successful combination of surgical and medical treatment in a case of spontaneous endomet…

Abstract Disorders of sexual development are rare in non‐human primates. We report a case of true hermaphroditism in a 19‐year‐old, nulliparous, female baboon ( Papio spp.). At necropsy, the animal was obese with adequate muscle mass and hy…

BACKGROUND: As endometriosis is known to be very painful in humans, therapeutic studies should consider pain-related aspects in experimental animals too. In a previous study, we found that common marmosets suffering from endometriosis show …

Abstract Background Human pleuro‐pulmonary endometriosis ( PPE ) is rare. Recently, we identified several cases of abdominal endometriosis in baboons that developed PPE . Materials and Methods Ten cases of PPE and four of intra‐abdominal en…

BACKGROUND: As common marmosets (Callithrix jacchus) are frequently used experimental animals, sensitive test systems are needed to evaluate impairment and pain caused by procedures and diseases. METHODS: A diurnal profile of healthy animal…

BACKGROUND: Ovarian pathology is an important cause of decreased fertility and reproductive capability and may impact multiple systems, particularly in aging rhesus macaques. METHODS: Retrospective histopathologic and immunohistochemical a…

BACKGROUND: Endometrial and cervical polyps are masses of endometrium or cervical epithelium that bulge into the uterine or cervical lumen. The physiopathology and contributing factors of endometrial polyps development are still unknown. ME…

BACKGROUND: Marmosets and tamarins are increasingly used in research, but their pathology remains poorly defined compared with Old World primates. METHODS: Necropsy records of 129 marmosets and 52 tamarins were reviewed; none was used expe…

BACKGROUND: Endometriosis is a condition where endometrium-like tissue forms lesions at ectopic sites outside the uterus. In women, oral contraceptive pills and progestins are often prescribed as therapy for early stage endometriosis. In co…

Abstract Background Spontaneous reproductive tract abnormalities occurred in six female wild‐caught, Philippine‐origin, Macaca fascicularis . These animals were between 19 and 22 years of age and maintained in captivity for approximately 15…

The National Institute on Aging (NIA) sponsored a workshop on September 8, 2004, to discuss the incidence, diagnosis, and clinical treatment of endometriosis in rhesus monkey colonies. Because of the growing number of aging studies using rh…

Spontaneous endometriosis was diagnosed in 43 baboons over a 14-year period. Thirty-seven have died; five remain alive; one was sold and lost to follow-up. The average age at diagnosis was 17.2 years; 29 (67%) were between 12 and 21 years o…

Twelve spontaneous ovarian tumors were found in the Southwest Foundation for Biomedical Research baboon colony. These included four granulosa cell tumors, three teratomas, two endometrioid carcinomas, one seromucinous cystadenofibroma, a cy…

A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described na…

Rhesus macaques (Macaca mulatta) with endometriosis were identified using reproductive histories, serum levels CA-125, pelvic ultrasonography, laparoscopy, and histopathology. All animals were evaluated from a large breeding colony and had …

This report describes a lesion resembling adenomyosis occurring in a Macaco mulatta with a gastric lignobezoar. A review of the literature suggests that this type of lesion is a common response of Macaco species to a variety of agents.