Endometrial and cervical polyps in 22 baboons (Papio sp.), 5 cynomolgus macaques (Macaca fascicularis) and one marmoset (Callithrix jacchus)

Melissa W Bennett, Edward J Dick, Natalia E Schlabritz-Loutsevitch, Natalia Schlabritz‐Loutsevitch, Juan Carlos López-Alvarenga, Juan C Lopez-Alvarenga, Priscilla C Williams, R Mark Sharp, Gene B Hubbard
Journal of medical primatology · 2009 · vol. 38(4) , pp. 257–262 · doi:10.1111/j.1600-0684.2009.00350.x · PMID:19281481 · PMC2729650 · W2133051179
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Endometrial polyps in baboons were associated with increased age, shorter menstrual cycles, and endometriosis, supporting their use as a model for studying human endometrial polyps.

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Abstract

BACKGROUND: Endometrial and cervical polyps are masses of endometrium or cervical epithelium that bulge into the uterine or cervical lumen. The physiopathology and contributing factors of endometrial polyps development are still unknown. METHODS: Clinical and pathology records of 28 non-human primates with histologically confirmed endometrial and cervical polyps were reviewed. Twenty-one baboons with endometrial polyps were evaluated for age at diagnosis, body weight, menstrual cycle length, presence of endometriosis and adenomyosis and number of offspring, cesarean sections, and stillbirths. RESULTS: Endometrial polyps in baboons were associated with increased age, decreased menstrual cycle lengths, endometriosis, and decreased parity. No differences were found for weight, adenomyosis, or number of cesarean sections or stillbirths. CONCLUSIONS: Baboons are a promising model for the study of endometrial polyps because of their similarity to humans in both the development of endometrial polyps and association of many of the same risk factors.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Monkey Diseases Polyps Uterine Cervical Diseases Uterine Diseases Animals Callithrix Female Macaca fascicularis Monkey Diseases Papio Polyps Polyps Uterine Cervical Diseases Uterine Cervical Diseases Uterine Diseases Uterine Diseases

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