Lyttle CR

No ORCID on file · 7 papers in corpus · active 1989-2004

Study types

  • article 6
  • other 1

Condition tags

  • endometriosis 7
  • chronic_pelvic_pain 1
  • infertility 1
  • endometrioma 1
article 2004
A selective estrogen receptor-β agonist causes lesion regression in an experimentally induced model of endometriosis
Human Reproduction ·doi:10.1093/humrep/deh711

BACKGROUND: Endometriosis is a common gynaecological problem of uncertain aetiology. It affects primarily young, reproductive-aged women and can result in chronic pelvic pain and infertility. Current approved therapies have significant side…

article 1997
Chemotaxis of macrophages by a peritoneal fluid protein in women with endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(97)81398-2

ObjectiveTo expand on a preliminary study comparing the chemotactic potential of peritoneal fluid (PF) from women with and without endometriosis and to characterize this activity via immunosuppressants and a protease.DesignCase control stud…

article 1994
Inflammatory changes of the endometrium in patients with minimal-to-moderate endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)57059-9

ObjectiveTo investigate the endometrium of normal patients for chemotactic activity to neutrophils and macrophages and compare these findings with those of patients with endometriosis.Study designEndometrial biopsies from patients with and …

article 1993
Increased chemotactic activity of peritoneal fluid in patients with endometriosis
American Journal of Obstetrics and Gynecology ·doi:10.1016/0002-9378(93)90500-i

ObjectiveOur purpose was to investigate the ability of the peritoneal fluid of patients with endometriosis to induce chemotaxis of neutrophils and macrophages.Study designPeritoneal fluid samples of patients with endometriosis (n = 20), nor…

article 1991
The effect of estradiol on the production and secretion of complement component 3 by the rat uterus and surgically induced endometriotic tissue
Fertility and Sterility ·doi:10.1016/s0015-0282(16)54135-1

We have recently demonstrated that glandular epithelial cells isolated from human endometriotic tissue synthesize and secrete complement component 3 (C3). Furthermore, because C3 is capable of producing many of the immunological activities …

other 1990
Endometrial synthesis and secretion of complement component-3 by patients with and without endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)53518-3

In the present study we examined complement-3 (C3) synthesis and secretion from early proliferative endometrium of infertile patients with and without endometriosis. One gram of tissue was obtained by endometrial sampling at the time of dia…

article 1989
Production and Secretion of Complement Component 3 by Endometriotic Tissue*
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem-69-5-1003

Many investigators have described a variety of immune phenomena associated with endometriosis. Among these are elevated titers of activated macrophages, monokines, and lymphokines in the peritoneal fluid of patients with endometriosis. In 1…