Guo H

BACKGROUND: Adenomyosis diagnosis and classification relies primarily on magnetic resonance imaging or pathological examination. Liquid biopsy has been widely applied in oncology but remains underexplored for adenomyosis. We aimed to identi…

Currently available classification criteria for obstetric antiphospholipid syndrome (OAPS) are often overly strict and may miss a considerable number of patients with so-called "non-criteria-defined OAPS". We aimed to establish a diagnostic…

BACKGROUND: Endometriosis (EMs) is often classified as a benign disease; however, it exhibits malignant biological characteristics. Collapsin Response Mediator Protein 4 (CRMP4) has been implicated in the regulation of cell migration and in…

Currently, hormonal therapy for endometriosis faces challenges in achieving a balance between treatment and preserving the chance of pregnancy. Therefore, the development of non-hormonal therapy holds significant clinical importance. Angiog…

BackgroundIn assisted reproductive technology, preventing premature ovulation is crucial for achieving successful pregnancy outcomes. The traditional GnRH antagonist protocol is commonly used to suppress the luteinizing hormone (LH) surge, …

Magnetic nanomaterials (MNMs) are nanoscale materials with inherent magnetic properties that can respond to external magnetic fields, typically composed of magnetic metals or metal oxides. These materials exhibit broad application prospects…

Abstract Endometriosis is a chronic gynecological condition influenced by inflammation and oxidative stress. Dietary vitamin B1 plays a role in reducing oxidative stress, which may influence endometriosis risk. However, limited research exp…

AIM: Adenomyosis and endometriosis are gynecological conditions with overlapping symptoms but distinct pathologies. Both affect the women's reproductive system, but their interrelation and shared clinical pathways are underexplored. This st…

OBJECTIVE: To analyze the correlation between Clinical Features and Perinatal Outcomes in the population of pregnancies with adenomyosis. METHODS: This retrospective study analyzed 413 pregnant women with ultrasonography/MRI-confirmed aden…

BackgroundIntussusception is the leading cause of acute abdominal conditions in infants, yet it is frequently under-recognised in those younger than 3 months, potentially resulting in serious complications such as bowel necrosis, peritoniti…

ObjectiveCurrently, it has been reported that uterine microbiota affected pregnancy outcomes in assisted reproductive technology, but little was known in obese women. Thus, this study aims to explore how body weight affects pregnancy outcom…

An increasing number of research have suggested that ferroptosis plays an important role in endometriosis (EMS). This study was to identify a ferroptosis-related diagnosis gene in EMS by using bioinformatics. R Bioconductor package limma wa…

OBJECTIVE: To investigate the association between lipid accumulation product (LAP) and endometriosis using data from the National Health and Nutrition Examination Survey (NHANES), because lipid metabolism alterations and obesity have been i…

Nuclear receptors (NRs) are a large family of ligand-dependent transcription factors that regulate the expression of a wide range of target genes in response to endogenous and exogenous ligands, including steroid hormones, thyroid hormone, …

BackgroundThe global health crisis of coronavirus disease 2019 (COVID-19) continues to impact people of all age groups worldwide. Recent studies increasingly support that COVID-19 infection may affect reproductive function, causing subferti…

Endothelial-mesenchymal transition (EndMT) is a biological process in which endothelial cells lose intercellular junctions and endothelial characteristics under specific pathophysiological stimuli and acquire mesenchymal traits. It plays a …

OBJECTIVE: Little is known about the role of timing of physical activity in female reproductive disorders. These disorders include polycystic ovary syndrome (PCOS), heavy menstrual bleeding (HMB), endometriosis, infertility, and pregnancy-r…

BACKGROUND: Endometriosis is a debilitating, chronic disease that affects approximately 10% of women of reproductive age worldwide. The most common symptom is chronic pelvic pain, which leads to a reduced quality of life and requires lifelo…

ObjectiveTo analyze the effect of autologous platelet-rich plasma (PRP) intrauterine perfusion on the clinical outcomes of frozen-thawed embryo transfer in patients with chronic endometritis.MethodsA retrospective continuous cohort of 219 p…

ObjectiveTo investigate whether vaginal and endometrial microbiota impact pregnancy outcomes in frozen embryo transfers (FET) during hormone replacement cycles.MethodsThis retrospective cohort study analyzed 51 first-time FET patients from …

BACKGROUND: Endometriosis, a complex gynecological condition, involves inflammation and immune dysregulation. The vaginal microbiota, characterized by its diversity, is an integral part of the vaginal microecology-interacting with vaginal a…

ObjectivesOur study tries to investigate the effect of the Mediterranean diet (MeDiet) on assisted reproductive treatment outcomes in women after COVID-19 infection.DesignA prospective observational cohort study in the Reproductive and Gene…