Extragenital endometriosis is common and may be found in any tissue. The most pronounced symptoms are pain and local bleeding that usually (at least initially) are cyclical and more pronounced at the time of menstruation. The lesions often …
Sciatic pain in a young woman was not relieved by orthopedic treatment. The gynecologist found a large hard tumor-like mass in the uterosacral ligament extending to the pelvic wall. Cytologic examination of fine needle aspirate indicated an…
A comparative histochemical study was performed on endometriotic tissue and uterine endometrium obtained simultaneously from the same patient. No difference in the amount and distribution of glycogen and acid and neutral polysaccharides was…
Estrogen and progesterone binding to endometriotic and endometrial tissue was studied histochemically using estradiol and progesterone fluorochrome derivatives (E2-bovine serum albumin-fluorescein isothiocyanate and progesterone-bovine seru…
In a histologic study of human endometrium transplanted into nude mice, eutopic endometrium from each of 8 women was transplanted subcutaneously to 4 nude mice, 1 of which was treated with polyestradiol phosphate, 1 with MPA, 1 with danazol…
In a study of the morphologic effects of various steroid hormones on human uterine endometrium and endometriotic tissue, specimens from 6 women were transplanted subcutaneously into 24 nude mice. In each case, specimens collected simultaneo…
A histochemical method for the detection of steroid-binding sites in very small tissue specimens was evaluated. Competitive binding experiments proved the method to be sufficiently specific. When applied to endometrium and endometriotic tis…
A comparative study on the histological appearance of endometrium and endometriotic tissue obtained simultaneously has been performed. In all, 47 endometriotic samples from 28 patients were examined. In 15 cases, samples from more than one …
One hundred and sixteen patients with laparoscopically confirmed primary or recurrent endometriosis were treated with danazol, either 600 mg daily for 4 months (group A, n = 76) or 600 mg daily for the first 2 months, followed by 400 mg dai…
In 12 women with menorrhagia (greater than or equal to 80 ml per menstrual period) a progesterone-releasing device (Progestasert) was inserted. The women were followed by repeated measurements of the blood loss for 12 periods. The menstrual…
Cytosol estrogen (ER) and progesterone (PR) receptors were assayed in peritoneal and ovarian endometriotic tissue from 20 patients. In 12 of the cases the intrauterine endometrium was assayed as well. The control material consisted of norma…