Histochemical localization of specific estrogen and progesterone binding in human endometrium and endometriotic tissue
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Abstract
A histochemical method for the detection of steroid-binding sites in very small tissue specimens was evaluated. Competitive binding experiments proved the method to be sufficiently specific. When applied to endometrium and endometriotic tissue obtained simultaneously from the same patient, a distinct binding was found both in the epithelial structures and in the stroma. The binding pattern in endometriotic glands resembled that in the endometrium. The study seems thus to support the conclusion that endometriotic lesions contain specific binding sites for estrogen and progesterone and that their distribution seems to be similar to that found in the endometrium from the same patient.
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References (6)
- Comparison of cytosol estrogen and progestin receptor status in malignant and benign tumors and tumor‐like lesions of human ovary via openalex
- Dating the Endometrial Biopsy via openalex
- Estrogen and Progesterone Cytosol Receptor Concentration in Endometriotic Tissue and Intrauterine Endometrium via openalex
- W1988244554 via openalex
- W2223229280 via openalex
- W2314595456 via openalex
Cited by (7)
- Cytosolic estrogen and progesterone receptor content in the endometriotic tissues and endometrium in women with and without endometriosis 2005
- Experimental model for endometriosis. Comparative histological study between the ectopic and eutopic endometrium 1997
- Receptor concentrations for estradiol and progesterone in surgically induced endometriosis in the rat 1994
- Diseases of the Peritoneum 1994
- Tissue Factors Influencing Growth and Maintenance of Endometriosis<sup>a</sup> 1991
- c-myc protooncogene polypeptide expression in endometriosis 1991
- Endometriosis, Lesions of the Secondary Müllerian System, and Pelvic Mesothelial Proliferations 1987
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- europepmc
- last seen: 2026-07-01T06:12:12.862213+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:09:55.985569+00:00
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