Eight subjects with normal menstrual cycles were treated with danazol (800 mg daily) during one luteal phase to assess the effect on follicular development in the subsequent cycle. Plasma levels of luteinizing hormone (LH), follicle-stimula…
The synthetic steroid, danazol [17 alpha-pregna-2,4-dien-20-yno-(2,3,d)isoxazol-17-ol], is used widely for the treatment of endometriosis. In nine subjects studied over a 6-month course of treatment and for 5 months subsequently, plasma hig…
We describe a problem in measuring serum testosterone concentrations in the serum of women who are taking danazol. The Diagnostic Products Corporation testosterone radioimmunoassay gives very high apparent testosterone concentrations in the…
Platelet count and platelet function have been studied in detail in 14 women before and during treatment with danazol for endometriosis. A progressive and highly significant increase in platelet count was recorded from the pretreatment valu…
Multiple sampling was carried out in 4 postmenopausal women for measurement of LH and FSH before and at the end of a 1-week treatment period with Danazol (400 mg daily). A small but significant depression of FSH was found in 3 of 4 subjects…
Spontaneous ovarian activity, as reflected by the urinary excretion of total estrogen and pregnanediol measured serially (thrice weekly) over a period of 3-4 months, was studied in nine young women (15-27 yr old) with a history of dysfuncti…
The time-domain nodal discontinuous Galerkin (TD-DG) method is emerging as a potential wave-based method for three-dimensional (3D) room acoustics modeling, where high-order accuracy, geometrical flexibility and accurate modeling of boundar…
The effects of danazol an antiogonadotropin derivative of ethisterone on the pituitary and ovarian function in the rhesus monkey were determined. Monkeys were administered danazol (30 mg/kg) from either Days 1-9 (Group 1 4 monkeys) 3-20 (Gr…
The dynamics of estrogen secretion and production were studied using isotope dilution techniques combined with direct sampling of ovarian venous blood and follicular fluid in 10 women with a clinical history of anovulatory dysfunctional ute…
Summary The occurrence of cystic glandular hyperplasia of the endometrium in adolescent girls has been reviewed. This condition has been diagnosed much less frequently in the South-Eastern Region of Scotland than in previously reported ser…
Summary The occurrence of cystic glandular hyperplasia of the endometrium in adolescent girls has been reviewed. This condition has been diagnosed much less frequently in the South‐Eastern Region of Scotland than in previously reported seri…