DANAZOL TREATMENT AND PLATELET FUNCTION

Ian S. Fraser, I S Fraser, J Burridge, Jill Burridge
The Medical journal of Australia · 1980 · vol. 1(7) , pp. 313–314 · doi:10.5694/j.1326-5377.1980.tb134878.x · PMID:7393057 · W90247855
article OA: closed CC0 ⤵ 4 in-corpus citations
View on OpenAlex View on PubMed View at publisher

Abstract

Platelet count and platelet function have been studied in detail in 14 women before and during treatment with danazol for endometriosis. A progressive and highly significant increase in platelet count was recorded from the pretreatment value (311 x 10(9)/L) to the value after six months of treatment (366 x 10(9)/L; P less than 0.001). Five patients developed minor platelet release defects, which may have been caused by the drug. However, the abnormalities shown are only likely to be of clinical importance in patients with preexisting platelet abnormalities.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Blood Platelets Danazol Pregnadienes Bleeding Time Blood Platelets Danazol Danazol Endometriosis Endometriosis Female Humans Platelet Adhesiveness Platelet Adhesiveness Platelet Aggregation Platelet Aggregation Platelet Count Pregnadienes

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (2)

Cited by (4)

References (7)

Cited by (4)

Source provenance

europepmc
last seen: 2026-06-23T06:15:44.889181+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:10:10.897782+00:00
License: CC0 · commercial use OK