Umbilical endometriosis: report of a case and its dermoscopic features*

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AI-generated summary by claude@2026-06, 2026-06-07

This paper reports a case of primary umbilical endometriosis and discusses its dermoscopic features, differential diagnoses, and management, emphasizing the need for endometriosis screening.

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AI-generated deep summary by claude@2026-06, 2026-06-07

This paper reports a single case of primary umbilical cutaneous endometriosis in a 32-year-old woman with a painful 3×3 cm shiny reddish-brown umbilical nodule that had enlarged over 3 months and intermittently varied in size, with one episode of spontaneous bleeding not linked to menses. Using polarized-light dermoscopy, the authors observed homogeneous localized reddish pigmentation without differentiated structures plus an amorphous brown area with a more evident skin network, and histopathology after biopsy showed fibroblastic dermal proliferation, endometrial glandular tissue with decapitation secretion, and hemosiderin deposits consistent with prior bleeding; imaging and Ca-125 were normal. A key limitation acknowledged by the authors is that dermoscopic features are not well established and their findings differed partially from the only prior published dermoscopy case, lacking the previously described “red atolls.” This paper is centrally about endometriosis — specifically primary umbilical cutaneous endometriosis and its dermoscopic and histopathologic features.

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Abstract

Cutaneous endometriosis is a rare manifestation of endometriosis, representing 0.5% to 1% of all endometriosis cases. It can be divided into primary and secondary, when appearing spontaneously or after a surgical procedure, when it is mostly found on surgical scar tissue. Some etiologies were proposed, but none of them could entirely explain the appearance of the tumor. Differential diagnosis includes melanoma, metastatic nodule, keloid and pyogenic granuloma. Dermoscopic features are not yet well established, but there are some characteristics that suggest the diagnosis. Treatment is surgical in larger sized lesions. Malignization can occur. The screening for endometriosis is mandatory by means of gynecologic, imaging and marked-tumor evaluation. We report a case of primary umbilical endometriosis and discuss its dermoscopic aspects.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Umbilicus Adult Biopsy Dermoscopy Diagnosis, Differential Endometriosis Female Humans Melanoma Melanoma Skin Neoplasms Skin Neoplasms Umbilicus

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (9)

Cited by (24)

Source provenance

europepmc
last seen: 2026-06-12T06:13:51.797165+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:19:05.543671+00:00
License: CC0 · commercial use OK