A Case of Spontaneous Umbilical Endometriosis

Jennifer J Law, Victoria C Kuritza
Cureus · 2026 · vol. 18(4) , pp. e107516 · doi:10.7759/cureus.107516 · PMID:42181319 · PMC13195408 · W7155224631
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report describes a young woman with a spontaneous umbilical nodule confirmed histopathologically as endometriosis, despite no signs of pelvic endometriosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 ⓘ

This paper reports a rare case of spontaneous umbilical endometriosis (Villar’s nodule) in a 29-year-old nulligravid woman with a painless, occasionally bleeding umbilical lesion and no prior abdominal surgery/trauma and no classic endometriosis symptoms. The lesion was excised and histopathology showed endometrial-type glands rimmed by endometrial-type stroma, confirming primary cutaneous endometriosis, while pelvic examination and transvaginal ultrasound found no pelvic endometriosis. A key limitation is that, as a single case report, it cannot establish prevalence or causal mechanism, and the patient’s broader disease status was assessed with imaging rather than definitive surgical mapping. This paper is centrally about endometriosis — specifically primary cutaneous umbilical endometriosis (Villar’s nodule) presenting without prior surgery or classic symptoms.

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Abstract

Umbilical endometriosis, also known as Villar's nodule, is an atypical manifestation of endometriosis. We present a rare case of spontaneous Villar's nodule in a young, nulliparous woman with no history of abdominal surgery or trauma who had no classic symptoms of endometriosis. Clinical examination revealed a painless umbilical nodule, and histopathologic evaluation demonstrated endometrial-type glands and stroma, confirming primary cutaneous endometriosis. Further gynecologic evaluation, including pelvic examination and transvaginal ultrasound, showed no evidence of pelvic endometriosis. We review proposed pathogenic mechanisms, discuss diagnostic considerations, and highlight the importance of prompt gynecologic referral. Early recognition with complete excision and appropriate gynecologic follow-up is essential, particularly in patients desiring future fertility.

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Condition tags

endometriosis

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