Hormonal contraceptives and endometriosis/adenomyosis
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⤵ 12 in-corpus citations
AI-generated summary
Hormonal contraceptives, particularly combined estrogen/progestogen and continuous progestogen-only therapies, are cost-effective treatments for various forms of endometriosis and adenomyosis.
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Abstract
Over the past 50 years hormonal contraceptives have gradually developed to be cost-effective medical treatment modalities for primary and secondary therapy of endometriosis/adenomyosis. This is particularly true for the various estrogen/progestogen combinations as monophasic - particularly progestogen-dominant - preparations in cyclic, long-cyclic and continuous treatment forms. An alternative is the progestogen-only therapy used continuously. Therapeutic effects have been shown for peritoneal, ovarian and deep-infiltrating endometriosis as well as for adenomyosis. An individualized, medical long-term treatment concept to control endometriosis/adenomyosis-related symptoms, endometriosis/adenomyosis development and minimizing the recurrence rate needs to be further studied in women, who do not desire to become pregnant.
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References (23)
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- Effects of the levonorgestrel-releasing intrauterine system on cell proliferation, Fas expression and steroid receptors in endometriosis lesions and normal endometrium via openalex
- [Hormone therapy of endometriosis--principles and clinical aspects of gestagen treatment]. via openalex
- Is There a Role for Use of Levonorgestrel Intrauterine System in Women with Chronic Pelvic Pain? via openalex
- Long-term cyclic and continuous oral contraceptive therapy and endometrioma recurrence: a randomized controlled trial via openalex
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- Non-contraceptive benefits of hormonal contraceptives. via openalex
- Non-contraceptive health benefits of oral contraceptives via openalex
- Non-contraceptive uses of levonorgestrel-releasing hormone system (LNG-IUS)—A systematic enquiry and overview via openalex
- Norethisterone acetate in the treatment of colorectal endometriosis: a pilot study via openalex
- Pathophysiology, diagnosis and treatment of endometriosis. via openalex
- Postoperative oral contraceptive exposure and risk of endometrioma recurrence via openalex
- Post-operative oral contraceptive use reduces the risk of ovarian endometrioma recurrence after laparoscopic excision via openalex
- Post-operative use of oral contraceptive pills for prevention of anatomical relapse or symptom-recurrence after conservative surgery for endometriosis via openalex
- Recurrence rate of endometrioma after laparoscopic cystectomy: A comparative randomized trial between post-operative hormonal suppression treatment or dietary therapy vs. placebo via openalex
- Reprint of Classification and pharmacology of progestins via openalex
- The evaluation of the effectiveness of an intrauterine-administered progestogen (levonorgestrel) in the symptomatic treatment of endometriosis and in the staging of the disease via openalex
- The LNG-IUS study on adenomyosis: a 3-year follow-up study on the efficacy and side effects of the use of levonorgestrel intrauterine system for the treatment of dysmenorrhea associated with adenomyosis via openalex
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Cited by (11)
- Safety and Efficacy of Radiofrequency Ablation for Abdominal Wall Endometriosis: A Single-center Experience 2026
- Comparison of Patients with Adenomyosis Detected in Hysterectomy Material and Patients with Other Benign Pathologies: Retrospective Study 2024
- Is high-intensity focused ultrasound a magical solution to endometriosis? A systematic review 2024
- Safety and efficacy of microwave ablation for abdominal wall endometriosis: A retrospective study 2023
- Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review 2021
- Abdominal wall endometriosis treatment by ultrasound-guided high-intensity focused ultrasound ablation: a case report 2018
- Ultrasound‐guided high‐intensity focused ultrasound treatment for abdominal wall endometriosis: a retrospective study 2017
- Current and Future Medical Treatment of Adenomyosis 2016
- <i>β</i> ‐Catenin activation contributes to the pathogenesis of adenomyosis through epithelial–mesenchymal transition 2013
- Adenomyosis: A Challenge in Clinical Gynecology 2012
- Application of Mini-abdominoplasty after Conservative Excision of Extensive Cesarean Scar Endometriosis 2012
Source provenance
- europepmc
- last seen: 2026-09-26T06:15:21.694264+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:16:54.825375+00:00
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