Medical treatment of endometriosis: a comparative trial.

Postgraduate medical journal · 1979 · vol. 55 Suppl 5 , pp. 37–9 · PMID:395519 · W2464670484
article OA: closed CC0 ⤵ 33 in-corpus citations
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AI-generated summary by claude@2026-06, 2026-06-09

Danazol proved superior to mestranol with norethynodrel for endometriosis, though surgery is needed for extensive disease, hysterectomy for severe symptoms in women who have completed childbearing, and danazol is indicated for young women with mild/moderate endometriosis or postoperatively.

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Abstract

In a comparison of danazol, and mestranol with norethynodrel (Enavid, Searle) in the treatment of endometriosis danazol was shown to be superior. Danazol is however relatively ineffective when large tumours or extensive adhesions are present and such patients will usually need a surgical operation. Women who have completed their families and who have severe symptoms will be better treated by hysterectomy. Treatment with danazol is indicated for young women with mild or moderate endometriosis. Danazol treatment may also be given postoperatively after conservative operations.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Danazol Endometriosis Genital Neoplasms, Female Pregnadienes Body Weight Body Weight Clinical Trials as Topic Danazol Danazol Drug Combinations Endometriosis Female Genital Neoplasms, Female Humans Mestranol Mestranol Norethynodrel Norethynodrel Pregnadienes

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (33)

Source provenance

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