Cutaneous endometriosis: diagnostic immunohistochemistry and clinicopathologic correlation

Farooq U, Uzma Farooq, Laureano AC, Ana C. Laureano, Mariya Miteva, Miteva M, Elgart GW, George W. Elgart
Journal of cutaneous pathology · 2011 · vol. 38(6) , pp. 525–528 · doi:10.1111/j.1600-0560.2011.01681.x · PMID:21352260 · W1964208213
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This report describes a rare case of cutaneous endometriosis in a 44-year-old woman, highlighting the diagnostic utility of immunohistochemistry with CD10, estrogen receptor, and progesterone receptor positivity.

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Abstract

Endometriosis is a condition where endometrial glands and stroma are ectopically located in sites other than the uterine cavity. Cutaneous endometriosis is very rare, representing approximately 1.1% of cases of extrapelvic endometriosis. We report a case of a 44-year-old female with no prior surgical history who presented with multiple tan brown periumbilical nodules. Histopathological examination revealed multiple glandular structures in the dermis with surrounding stroma. Immunohistochemistry cinches the diagnosis, as CD10, estrogen receptor and progesterone receptor are strongly positive in our case. The mainstay of treatment of cutaneous endometriosis is surgical excision of the lesion.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Skin Diseases Adult Adult Endometriosis Endometriosis Endometriosis Female Female Humans Humans Immunohistochemistry Immunohistochemistry Skin Diseases Skin Diseases Skin Diseases

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (16)

Cited by (10)

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