Cutaneous endometriosis: diagnostic immunohistochemistry and clinicopathologic correlation
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This report describes a rare case of cutaneous endometriosis in a 44-year-old woman, highlighting the diagnostic utility of immunohistochemistry with CD10, estrogen receptor, and progesterone receptor positivity.
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Abstract
Endometriosis is a condition where endometrial glands and stroma are ectopically located in sites other than the uterine cavity. Cutaneous endometriosis is very rare, representing approximately 1.1% of cases of extrapelvic endometriosis. We report a case of a 44-year-old female with no prior surgical history who presented with multiple tan brown periumbilical nodules. Histopathological examination revealed multiple glandular structures in the dermis with surrounding stroma. Immunohistochemistry cinches the diagnosis, as CD10, estrogen receptor and progesterone receptor are strongly positive in our case. The mainstay of treatment of cutaneous endometriosis is surgical excision of the lesion.
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Cited by (11)
- Cutaneous Deciduosis: A Rare Cutaneous Lesion Mimicking Malignancy 2024
- Atypical Sites of Endometriosis: Primary Inguinal Cutaneous Endometriosis 2023
- Skin endometriosis: A case report and review of the literature 2021
- Endometriosis of the Eyelid, an Extraordinary Extra-abdominal Location Highlighting the Spectrum of Disease 2019
- Endometriosis de la pared abdominal: estudio descriptivo de una serie de 21 casos 2019
- Extrapelvic Endometriosis: A Systematic Review 2019
- Primary umbilical endometriosis: a case report. 2017
- Cutaneous Endometriosis 2017
- Painful nodule in the caesarean section scar of a young woman 2015
- Cutaneous Decidualized Endometriosis in a Nonpregnant Female 2012
- Cutaneous deciduosis: a report of two cases of an unusual pseudomalignancy 2012
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- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:16:48.482574+00:00
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