Dysfunctional uterine bleeding

B H Chen, Chen BH, Giudice LC, L C Giudice, Linda C. Giudice
The Western journal of medicine · 1998 · vol. 169(5) , pp. 280–4 · PMID:9830356 · PMC1305317 · W1797777517
Review OA: closed CC0 ⤵ 8 in-corpus citations
📄 Open PDF View on OpenAlex View on PubMed
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This paper reviews dysfunctional uterine bleeding, defining it as abnormal uterine bleeding without a clear cause and outlining medical and surgical treatment options and their limitations.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Abnormal uterine bleeding is a common, debilitating condition. Dysfunctional uterine bleeding (DUB) is the diagnosis given to women with abnormal uterine bleeding in whom no clear etiology can be identified. DUB has been observed in both ovulatory and anovulatory cycles. Medical treatments include nonsteroidal anti-inflammatory drugs, oral contraceptive pills, progestins, danazol (a synthetic androgen), GnRH agonists, and antifibrinolytic drugs. The drawback to medical therapy, in addition to side effects, is that the benefit lasts only while the patient takes the medication. Surgical options have concentrated mainly on endometrial ablation and hysterectomy, and it is unclear whether one is superior to the other in terms of long-term outcome and patient satisfaction. Newer and less invasive ablation techniques, such as thermal balloon ablation, offer more treatment alternatives.

My notes (saved in your browser only)

MeSH descriptors

Menorrhagia Adolescent Adult Antifibrinolytic Agents Antifibrinolytic Agents Antifibrinolytic Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal Contraceptives, Oral Contraceptives, Oral Contraceptives, Oral Danazol Danazol Danazol Endometrium Endometrium Estrogen Antagonists Estrogen Antagonists Estrogen Antagonists

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (30)

Cited by (5)

Source provenance

europepmc
last seen: 2026-10-04T09:26:46.659050+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T22:00:48.437354+00:00
License: CC0 · commercial use OK