Chinese Herbal Medicine for Dysfunctional Uterine Bleeding: A Meta‐Analysis

Xiang Tu, Huang Gaomin, Shengkui Tan
In: Evidence-Based Complementary and Alternative Medicine · 2007 · vol. 6(1) , pp. 99–105 · doi:10.1093/ecam/nem063 · PMID:18955223 · W2172206415
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This meta-analysis of four low-quality trials found Chinese herbal medicine to be comparably effective to conventional western medicine for dysfunctional uterine bleeding, with no serious adverse events reported.

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Abstract

We conducted a systematic review to evaluate the efficacy and safety of Chinese herbal medicine (CHM) for dysfunctional uterine bleeding (DUB) by performing a meta-analysis. Randomized controlled trials (RCTs) or quasi-RCTs comparing CHM vs no treatment, placebo, conventional western medicine (CWM), or general non-specific surgical treatment for DUB were identified by electronic and manual searches. Trials of CHM treatments with CWM treatments were compared with CWM treatments alone. Jadad scale and allocation concealment were used to assess the quality of included studies. Four RCTs or quasi-RCTs involving 525 patients were included. The methodological quality was poor in all trials except one trial. No serious adverse events were reported in the included studies. With the lack of trials comparing CHM with no treatment or placebo, it is impossible to accurately evaluate the efficacy of CHM. However, CHM in these studies seem to show an encouraging comparative effectiveness with CWM. More RCTs with a higher quality are required.

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