Extremely elevated serum CA-125 level as a result of unruptured unilateral endometrioma: the highest value reported

Kahraman K, Korhan Kahraman, Ozguven I, Irem Ozguven, Mete Gungor, Mete Güngör, Cem Somer Atabekoğlu, Cem Somer Atabekoglu, Atabekoglu CS
Fertility and sterility · 2007 · vol. 88(4) , pp. 968.e15–968.e17 · doi:10.1016/j.fertnstert.2006.12.076 · PMID:17544420 · W2047933106
Case report OA: bronze CC0 ⤵ 14 in-corpus citations
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This case report details an exceptionally high serum CA-125 level in a patient with an unruptured unilateral endometrioma, representing the highest value previously documented for this condition.

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Abstract

OBJECTIVE: To present a case of a unilateral endometrioma with extremely elevated serum CA-125 levels. DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 25-year-old woman with left adnexal mass and extremely elevated serum CA-125 level, 7,900 U/mL, underwent laparoscopy. There were unilateral endometrioma and stage IV endometriosis. INTERVENTION(S): Laparoscopic excision of the endometrioma, unilateral salpingectomy, adhesiolysis, ablation of endometriotic foci, and partial omentectomy were performed, and histopathologic results confirmed the diagnosis of endometriosis. MAIN OUTCOME MEASURE(S): Extremely elevated serum CA-125 levels and unruptured ovarian endometrioma. RESULT(S): On the second, sixth, and 13th days of the menstrual period, serum CA-125 levels were 7,900 U/mL, 1,577 U/mL, and 627 U/mL, respectively. On the third postoperative day serum CA-125 level was 56 U/mL. CONCLUSION(S): Ovarian endometrioma and advanced endometriosis may be associated with extremely elevated serum CA-125 levels. For this reason ovarian endometrioma should be considered with respect to differential diagnosis of reproductive-age women presenting with an ovarian mass even if it resembles an ovarian malignancy.

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Condition tags

endometriosisendometrioma

MeSH descriptors

CA-125 Antigen Endometriosis Adult Adult CA-125 Antigen CA-125 Antigen Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Female Female Humans Humans Menstruation Menstruation Menstruation

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References (13)

Cited by (14)

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License: CC0 · commercial use OK