Endometriosis and its relationship with female infertility: an integrative review

In: Research, Society and Development · 2022 · vol. 11(15) , pp. e278111535707 · doi:10.33448/rsd-v11i15.35707 · W4309547004
article OA: diamond CC0 ⤵ 1 in-corpus citation
AI-generated summary by claude@2026-06, 2026-06-12

This integrative review of literature from 2016-2022 analyzes the relationship between endometriosis and female infertility, emphasizing early diagnosis and treatment's impact on women's health.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text

This integrative literature review assessed the relationship between endometriosis and female infertility using articles published between 2016 and 2022, organized into categories addressing the association with infertility, early diagnosis (including questionnaire and laboratory-test approaches), and treatment impacts on women’s health. Across the selected empirical studies, the review’s conclusion emphasized that care for women with endometriosis should pay attention to early diagnosis and to treatment, in relation to women’s quality of life. A major limitation is that, as an integrative review with heterogeneous included studies, it synthesizes existing literature rather than providing new primary data or a single standardized analytic method. This paper is centrally about endometriosis — it reviews how endometriosis relates to female infertility.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

This article presents an integrative literature review aimed at reviewing the relationship between endometriosis and female infertility between the years 2016-2022. In this type of study, the integrative review helps to obtain, identify and analyze a specific topic in the literature. Thus, the objective of this work is to extract information from the updated literature through articles selected between the years 2016-2022 in empirical categories called: “Relationship of endometriosis with female infertility”; “Early diagnosis of endometriosis and the influence on female infertility”; "Treatment of endometriosis and the impact on women's health", in order to relate endometriosis to female infertility in an integrative review. The conclusion is, therefore, that health professionals, who manage the treatment of endometriosis, should be attentive to early diagnosis, whether in the form of a questionnaire or laboratory tests, treatment and, consequently, the quality of women's life.
Full text 6,680 characters · extracted from oa-doi-fallback · click to expand
Endometriosis and its relationship with female infertility: an integrative review DOI: https://doi.org/10.33448/rsd-v11i15.35707Keywords: Endometriosis, Diagnostic, Woman, Infertility.Abstract This article presents an integrative literature review aimed at reviewing the relationship between endometriosis and female infertility between the years 2016-2022. In this type of study, the integrative review helps to obtain, identify and analyze a specific topic in the literature. Thus, the objective of this work is to extract information from the updated literature through articles selected between the years 2016-2022 in empirical categories called: “Relationship of endometriosis with female infertility”; “Early diagnosis of endometriosis and the influence on female infertility”; "Treatment of endometriosis and the impact on women's health", in order to relate endometriosis to female infertility in an integrative review. The conclusion is, therefore, that health professionals, who manage the treatment of endometriosis, should be attentive to early diagnosis, whether in the form of a questionnaire or laboratory tests, treatment and, consequently, the quality of women's life. References Araújo, F. W. C., Schmidt, D. B. (2020). Endometriose um problema de saúde pública: revisão de literatura. Revista Saúde e Desenvolvimento, 14(18), 25-37. Ashrafi, M., Jahanian Sadatmahalleh, S., Akhoond, M. R., Talebi, M. (2016). Evaluation of risk factors associated with endometriosis in infertile women. International Journal of Fertility and Sterility,10(1), 11–21. Barbosa, D. A. S., Oliveira, A. M. (2015). Endometriose e seu impacto na fertilidade feminina. Saúde & Ciência Em Ação, 1(1), 43-56. Cranney, R., Condous, G., Reid, S. (2017). An update on the diagnosis, surgical management, and fertility outcomes for women with endometrioma. Acta Obstetricia et Gynecologica Scandinavica, 96(6), 633–643. Duarte, A. N., Righi, M. G. (2021). A associação entre endometriose e infertilidade feminina: uma revisão de literatura. Acta Elit Salutis- AES. 4(1). Duccine, E. C. et al. (2019) Endometriose: uma causa da infertilidade feminina e seu tratamento. Revista Caderno de Medicina. 2(2). Fuldeore, M. J., Soliman, A. M. (2017). Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women. Gynecologic and Obstetric Investigation, 82(5), 453–461. Gordts, S., Koninckx, P., Brosens, I. (2017). Pathogenesis of deep endometriosis. Fertil Steril, 108, 872-85. Hodgson, R. M., Lee, H. L., Wang, R., Mol, B. W., Johnson, N. (2020). Interventions for endometriosis-related infertility: a systematic review and network meta-analysis. Fertility and Sterility, 113(2), 374-382. Nácul, A. P., Spritzer, P. M. (2010). Aspectos atuais do diagnóstico e tratamento da endometriose. Revista brasileira de ginecologia & obstetrícia. 32(6), 298-307. Miller J. E et al. (2017). Implications of imune dysfunction on endometriosis associated infertility. Oncotarget. 8(4). Oliveira, R et al. (2015). Perfil epidemiológico das pacientes inférteis com endometriose. Reprodução & Climatério, 30(1), 5-10. Panir, K. et al. (2018) Non-coding RNAs in endometriosis: a narrative review. Human Reproductive Update. 24(4), 497-515. Rodrigues, Marina et al. (2020). Clinical aspects and the quality of life among women with endometriosis and infertility: A cross-sectional study. BMC Women’s Health, 20(1), 1–7. Rolla, E. (2019). Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment. F1000research, 8, 529. Saha, R., Marions, L., Tornvall, P. (2017). Validity of self-reported endometriosis and endometriosis-related questions in a Swedish female twin cohort. Fertility and Sterility, 107 (1), 174- 178. São Bento, P. A. D. S, Moreira, M. C. N. (2017). A experiência de adoecimento de mulheres com endometriose: narrativas sobre violência institucional. Ciência & Saúde Coletiva, 22, 3023-3032. Sampson, J. A. (1927). Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity. American Journal of Obstetrics & Gynecology, 14(4), 422-469. Soliman, A. M., Surrey, E., Bonafede, M., Nelson, J. K., & Castelli-Haley, J. (2018). Real-World Evaluation of Direct and Indirect Economic Burden Among Endometriosis Patients in the United States. Advances in Therapy, 35(3), 408–423. Souza G. K. T. et al. (2017). Endometriose x infertilidade: revisão de literatura. Encontro de Extensão, Docência e Iniciação Científica (EEDIC), 3(1). Torres, J. I. S. L. et al. (2021). Endometriose, dificuldades no diagnóstico precoce e a infertilidade feminina: Uma Revisão. Research, Society and Development, 10(6). Tandoi. I et al. (2011). High rate of endometriosis recurrence in young women. Journal of pediatric and adolescent gynecology, 24(6), 376-379. Tanbo T, Fedorcsak P. (2017). Endometriosisassociated infertility: aspacts of pathophysiological mechanisms and treatment options. Acta Obstetricia et Gynecologica Scandinavica. 659- 67. Vercellini, P. et al. (2014). Adenomyosis and reproductive performance after surgery for rectovaginal and colorectal endometriosis: a systematic review and meta-analysis. Perod Biomed Online, 28, 704-13. Vieira, G. C. D et al. (2020). Endometriose: causas, implicações e tratamento da infertilidade feminina através das técnicas de reprodução assistida. Research, Society and Development, 9(10), e6859109128-e6859109128. Downloads Published Issue Section License Copyright (c) 2022 Veronica Arruda Barreto Souza; Aline Morais Fontenele ; Julia Rocha Vargens; Thais Camila Alves Lessa Duran This work is licensed under a Creative Commons Attribution 4.0 International License. Authors who publish with this journal agree to the following terms: 1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. 2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. 3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosisinfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (15)

Cited by (1)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK