Intestinal metaplasia and colonization of endometriosis in a case of an appendiceal mucinous neoplasm

Louis Libbrecht, Christophe Snauwaert, Martine De Vos, Karel Geboes, Claude Cuvelier, Liesbeth Ferdinande
Virchows Archiv : an international journal of pathology · 2012 · vol. 461(2) , pp. 227–229 · doi:10.1007/s00428-012-1264-5 · PMID:22735893 · W1973789505
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This case study examines intestinal metaplasia and endometriosis colonization within an appendiceal mucinous neoplasm, highlighting potential diagnostic challenges.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This paper reports a case in which intestinal metaplasia and colonization by endometriosis were observed in association with an appendiceal mucinous neoplasm. At a high level, the authors describe the pathologic findings in the resected specimen, emphasizing how endometriotic tissue can involve intestinal/colonic-type mucosa in a way that may be misinterpreted as invasive mucinous carcinoma, building on previously reported diagnostic pitfalls. The major limitation is that it is a single case report, so no generalizable frequency, mechanism, or outcome data are provided. This paper is centrally about endometriosis — it specifically describes endometriosis colonizing intestinal/metaplastic mucosa in the setting of an appendiceal mucinous neoplasm.

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References Yantiss RY, Clement PB, Young RH (2001) Endometriosis of the intestinal tract. A study of 44 cases of a disease that may cause diverse challenges in clinical and pathologic evaluation. Am J Surg Pathol 25:445–454 Driman DK, Melega DE, Vilos GA, Plewes EA (2000) Mucocele of the appendix secondary to endometriosis. Report of two cases, one with localized pseudomyxoma peritonei. Am J Clin Pathol 113:860–864 Pai RK, Beck AH, Norton JA, Longacre TA (2009) Appendiceal mucinous neoplasms. Clinicopathologic study of 116 cases with analysis of factors predicting recurrence. Am J Surg Pathol 33:1425–1439 Ponsford Tipps AM, Weidner N (2011) Colonization of intestinal endometriosis by benign colonic mucosa: a pattern potentially misdiagnosed as invasive mucinous carcinoma. Int J Surg Pathol 19:259–262 Mai KT, Burns BF (1999) Development of dysplastic mucinous epithelium from endometriosis of the appendix. Histopathology 35:368–372 Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Libbrecht, L., Snauwaert, C., De Vos, M. et al. Intestinal metaplasia and colonization of endometriosis in a case of an appendiceal mucinous neoplasm. Virchows Arch 461, 227–229 (2012). https://doi.org/10.1007/s00428-012-1264-5 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00428-012-1264-5

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma, Mucinous Appendiceal Neoplasms Endometriosis Intestines Adenocarcinoma, Mucinous Adenocarcinoma, Mucinous Appendiceal Neoplasms Appendiceal Neoplasms Endometriosis Endometriosis Female Humans Intestines Metaplasia Middle Aged

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (6)

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