Adenocarcinoma Ex–Goblet Cell Carcinoid of the Appendix With Metastatic Peritoneal Spread to Meckel’s Diverticulum and Endometriosis
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This case report details an appendiceal adenocarcinoma ex-goblet cell carcinoid with metastatic peritoneal spread to a Meckel's diverticulum and pelvic endometriosis, a rare presentation of this appendiceal malignancy.
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Abstract
Adenocarcinoma ex-goblet cell carcinoid is a very rare and histologically unique appendiceal malignancy with dual glandular and neuroendocrine differentiation. There is a high incidence of this tumor among middle-aged women with metastasis to the gynecologic tract with the mode of metastasis following peritoneal spread rather than hematogenous distribution. Adenocarcinoma ex-goblet cell carcinoid can spread to any peritoneal site including ovaries or omentum. We report a 37-year-old healthy woman who initially presented with right lower quadrant abdominal pain and pseudomyxoma peritonei. Histopathology of the appendectomy specimen revealed an adenocarcinoma ex-goblet cell carcinoid, signet ring cell type. Follow-up right hemicolectomy, omentectomy, bilateral salpingo-oophorectomy, and regional peritoneal resections revealed metastatic involvement by adenocarcinoma ex-goblet cell carcinoid, signet ring cell type. In this report, we describe a case of appendiceal adenocarcinoma ex goblet cell carcinoid with metastases to Meckel's diverticulum and areas of pelvic endometriosis, which have not been previously reported.
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Cites (2)
- Colonization of Intestinal Endometriosis by Benign Colonic Mucosa: A Pattern Potentially Misdiagnosed as Invasive Mucinous Carcinoma 2010
- Intestinal metaplasia and colonization of endometriosis in a case of an appendiceal mucinous neoplasm 2012
Cited by (1)
References (9)
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Cited by (1)
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- europepmc
- last seen: 2026-06-21T06:12:49.409960+00:00
- openalex
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- pubmed
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- unpaywall
- last seen: 2026-06-20T06:35:16.286784+00:00
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