Magnetic resonance imaging T2WI hyperintense foci number and the prognosis of adenomyosis after high‐intensity focused ultrasound treatment

Cheng-Chao Du, Du CC, Chengchao Du, Yu‐qi Wang, Yu-Qi Wang, Wang YQ, Dacheng Qu, Da-Cheng Qu, Qu DC, Liu-Peng Jiang, Jiang LP, Liu‐peng Jiang, Xin Yu, Yu X, Honggui Zhou, Hong-Gui Zhou, Zhou HG
International Journal of Gynecology & Obstetrics · 2021 · vol. 154(2) , pp. 241–247 · doi:10.1002/ijgo.13587 · PMID:33421123 · W3121041138
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A higher number of T2WI hyperintense foci in adenomyosis patients treated with HIFU was associated with worse symptom scores and lower ablation rates.

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Abstract

OBJECTIVE: To investigate the relationship between the number of hyperintense foci of T2-weighted imaging (T2WI) and the efficacy of high-intensity focused ultrasound (HIFU) in the treatment of adenomyosis. METHODS: This prospective cohort study enrolled 102 patients with adenomyosis. Participants were classified into two groups: 50 patients in whom the number of hyperintense foci on magnetic resonance imaging (MRI) T2WI was more than five were placed in the >5 group and 52 patients in whom the number of hyperintense foci on MRI T2WI was five or fewer were placed in the ≤5 group. Uterine fibroid symptoms (UFS) and visual analog scale (VAS) scores were recorded as indicators for the course of adenomyosis treatment. RESULTS: Among the enrolled patients, 84 received HIFU treatment and were followed up. At 6, 12, 24, and 36 months after HIFU treatment, the UFS score of women in the >5 group was higher than that of the patients in the ≤5 group (P 5 group (P < 0.05). CONCLUSION: Number of MRI T2WI hyperintense foci is a factor affecting the ablation rate and the clinical efficacy of HIFU treatment in women with adenomyosis. It is likely to be a predictor of the efficacy of HIFU in adenomyosis treatment.

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Outcome instruments

VAS-pain

Condition tags

adenomyosis

MeSH descriptors

Adenomyosis High-Intensity Focused Ultrasound Ablation Leiomyoma Magnetic Resonance Imaging Adenomyosis Adult Cohort Studies Female High-Intensity Focused Ultrasound Ablation Humans Leiomyoma Magnetic Resonance Imaging Middle Aged Prospective Studies Treatment Outcome

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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