Analise da influência de determinados alimentos no controle da endometriose e os pontos positivos e negativos do tratamento medicamentoso: uma revisão narrativa

In: Research, Society and Development · 2021 · vol. 10(15) , pp. e213101522438 · doi:10.33448/rsd-v10i15.22428 · W3217773249
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This narrative review found that certain foods, like beef and citrus fruits, may influence endometriosis risk, and hormonal treatments like dienogest and etonogestrel offer symptom relief but have limitations and potential side effects.

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This narrative bibliographic review assessed scientific evidence regarding potential benefits and harms of specific foods for controlling endometriosis and also analyzed strengths and weaknesses of hormonal pharmacological treatment. Using a PubMed/MEDLINE search with DeCS terms focused on endometriosis and nutrition (excluding pregnancy) and hormonal approaches, the authors selected 11 articles; among the findings, higher beef consumption was associated with a 56% increase in endometriosis diagnosis, while citrus fruit consumption was associated with a 22% reduction in risk. The review reports that dienogest 2 mg improved dysmenorrhea and preserved fertility, with the authors noting its safe use is for less than 65 weeks, and that etonogestrel implants were linked to reduced pelvic pain after 12–24 months but had high removal rates due to side effects. This paper also indicates a limitation typical of narrative reviews—synthesis of heterogeneous studies without systematic, exhaustive weighting of evidence—and it is centrally about endometriosis control, including dietary factors and the positive and negative aspects of medication.

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Abstract

Objetivos: Descrever as evidências científicas dos benefícios e malefícios de determinados alimentos no controle da endometriose e analisar os principais pontos positivos e negativos do tratamento hormonal. Metodologia: Revisão bibliográfica narrativa, com busca dos trabalhos na base de dados virtuais Pubmed/Medline utilizando os termos e Descritores em Ciências da Saúde (DeCS): endometriosis AND nutrition NOT pregnancy e endometriosis AND Contraceptives, Hormonal NOT pregnancy no idioma inglês. Foram selecionados 11 artigos que se encaixavam ao tema. Resultados: um estudo demonstrou que o consumo de duas porções de carne bovina se associava a um aumento de 56% no diagnóstico de endometriose enquanto outro trabalho concluiu que o consumo de frutas cítricas diminui em 22% o risco de se ter endometriose. A respeito do tratamento farmacológico, o dienogest 2 mg foi associado a melhora dos sintomas da dismenorreia e a preservação da fertilidade, porém seu uso seguro é por período menor que 65 semanas. Niu et al. (2021) observou que após um período de 12 a 24 meses as pacientes com o etonogestrel implante tendem a ter ausência de dor pélvica porém, o uso dessa medicação evoluiu com alta taxa de remoção devido seus efeitos colaterais. Conclusão: o tratamento da endometriose tem diversas opções e este deve ter sua escolha pautada na particularidade que cada mulher apresenta diante da sua tolerabilidade e grau de incomodo com cada medicação e a importância da abordagem multiprofissional no tratamento da endometriose.
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Objectives

Describe the scientific evidence of the benefits and harms of some foods in controlling endometriosis and analyze the main strengths and weaknesses of hormonal treatment. Methodology: Narrative bibliographic review, with search for publishies in the Pubmed/Medline virtual database using the terms and Descriptors in Health Sciences (DeCS): endometriosis AND nutrition NOT pregnancy and endometriosis AND contraceptives, Hormonal NOT pregnancy in English. Eleven articles that natch the theme were selected. Results: A study showed that the consumption of two portions of beef was associated with a 56% increase in the diagnosis of endometriosis while another study found that the consumption of citrus fruits reduced the risk of having endometriosis by 22%. Regarding pharmacological treatment, dienogest 2 mg was associated with improvement in dysmenorrhea symptoms and preservation of fertility, but its safe use is for a period of less than 65 weeks. Niu et al. (2021) observed that after a period of 12 to 24 months, patients with etonogestrel implant tend to have no pelvic pain, however, the use of this medication evolved with a high removal rate due to its side effects. Conclusion: the treatment of endometriosis has several options and the choice of one of these should be based on the particularity that each woman presents in front of their tolerability and degree of discomfort with each medication and the importance of a multidisciplinary approach in the treatment of endometriosis.

References

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