Fear of progression, imagery, interpretation bias, and their relationship with endometriosis pain
Observational
OA: closed
CC0
⤵ 9 in-corpus citations
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This study found that fear of progression, imagery, and interpretation bias were associated with increased fear of progression and greater pain interference in women with endometriosis.
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Abstract
Endometriosis is a chronic gynaecological condition, of which pain is both the most common and most debilitating symptom. As with other forms of pain, there is increasing recognition of the role of psychological processes in bridging the gap between pain and pain impact, and yet these processes are not well understood in endometriosis. The aim of this study was to investigate the relevance of fear of progression, imagery, and interpretation bias in endometriosis, and their contribution to pain interference. A total of 221 participants (mean age = 38 years, SD = 7.8) with endometriosis were recruited from Endometriosis Australia. This cross-sectional study included relevant demographics and endometriosis characteristics; questionnaires to measure fear of progression, imagery, interpretation bias, and pain; and the word association task to measure interpretation bias. Participants reported high scores on the Fear of Progression Questionnaire (M = 38/60), higher than that has been found in cancer. Controlling for age and pain intensity, we found that imagery, interpretation bias, and their interaction were associated with increased fear of progression and that fear of progression was associated with greater pain-related interference. In exploratory analysis, we also found that the frequency and distress of endometriosis-related intrusive imagery were associated with greater fear of progression and pain interference, after controlling for age and pain intensity. These findings provide the first support of the importance of fear of progression in people with endometriosis and suggest possible pathways for causal investigation.
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Cited by (11)
- Factors Influencing Fear of Progression in Endometriosis: A Path Analysis Using the Common-Sense Model 2026
- Endometriosis and ovarian cancer: epidemiological evidence, molecular insights, and clinical decision-making 2026
- Correlates of body image in individuals with endometriosis: The role of body compassion and endometriosis-related symptoms 2026
- Do Individuals With Endometriosis Display Interpretation and Memory Recall Biases Compared With Pain‐Free Controls? A Cross‐Sectional Study 2026
- The endometriosis pain course: Exploring predictors of clinical response to an internet-delivered psychological pain management program for endometriosis 2026
- Exploring the Immediate Effects of an Online Self-Regulation Intervention on Pain, Affect, and Arousal in Women with Endometriosis: An Observational Study Protocol 2025
- Bringing Endometriosis to the Road of Contemporary Pain Science 2025
- Impact of Therapeutic Interventions on Fear of Progression in Patients with Endometriosis 2025
- Experience of endometriosis pain: a qualitative study 2025
- Causal associations between sleep disorders and endometriosis: A Mendelian randomization analysis 2025
- Fear of progression, depression, and sleep difficulties in people experiencing endometriosis-pain: A cross-sectional study 2024
Source provenance
- europepmc
- last seen: 2026-10-10T06:11:15.153948+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-10T06:10:00.722175+00:00
License: CC0
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