Massive ascites as a presentation in a young woman with endometriosis: a case report

Case report OA: closed CC0 ⤵ 19 in-corpus citations
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This case report describes a young woman whose initial presentation of endometriosis was massive ascites, a rare but possible manifestation of the condition.

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Abstract

OBJECTIVE: To report a case of endometriosis associated with massive ascites and an elevated CA-125 level. DESIGN: Case report. SETTING: Tertiary care center. PATIENT(S): A 26-year-old woman presented with massive ascites and an increased CA-125 level suggestive of ovarian cancer. INTERVENTION(S): Ultrasonography, laparotomy, and bilateral ovarian cystectomy and reconstruction. Endometriosis was diagnosed postoperatively on the basis of histopathology. The patient received 6 months of treatment with a GnRH analogue. MAIN OUTCOME MEASURE(S): Ultrasound examination 6 months after surgery to evaluate for ascites or recurrent ovarian cysts. RESULT(S): Frozen sections obtained at laparotomy and ovarian cystectomy ruled out a malignancy. The final histologic report was compatible with a diagnosis of endometriosis. After 6 months of treatment with the GnRH analogue, the patient experienced a progressive reduction of the ascitic fluid and full remission after 2 years. CONCLUSION(S): Endometriosis associated with massive bloody ascites is an unusual occurrence. This report draws attention to this condition as a complication of endometriosis. For this reason, endometriosis should be included in the differential diagnosis of reproductive-age women presenting with an apparent ovarian malignancy.

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Condition tags

endometriosis

MeSH descriptors

Ascites Endometriosis Ovarian Cysts Ovarian Neoplasms Adult Adult Ascites Ascites Ascites Ascites CA-125 Antigen CA-125 Antigen CA-125 Antigen Diagnosis, Differential Diagnosis, Differential Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (41)

Cited by (20)

Source provenance

europepmc
last seen: 2026-10-12T06:17:10.165071+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:05:43.569505+00:00
License: CC0 · commercial use OK