Endometriosis mimicking advanced ovarian cancer

article OA: bronze CC0 ⤵ 33 in-corpus citations
AI-generated summary by claude@2026-06, 2026-06-28

This case report details a patient presenting with endometriosis that mimicked advanced ovarian cancer, highlighting the importance of considering benign conditions in the differential diagnosis of suspected malignancies.

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Abstract

ObjectiveTo report a case of endometriosis associated with massive ascites, pleural effusion, and extremely elevated Ca-125.DesignCase report.SettingUniversity hospital.Patient(s)A 46-year-old, white nulligravida with bilateral adnexal masses, Ca-125 of 3,504 U/mL, abdominal pain, ascites, and a pleural effusion.Intervention(s)Chemotherapy followed by exploratory laparotomy for suspected ovarian cancer.Main outcome measure(s)Surgical findings and histopathology.Result(s)Intraoperative examination and histology ruled out malignancy but found stage IV endometriosis.Conclusion(s)In rare instances advanced endometriosis may be associated with ascites, pleural effusions, and large pelvic masses. For this reason endometriosis should be included in the differential diagnosis of reproductive-age women presenting with apparent ovarian malignancy.

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Condition tags

endometriosis

MeSH descriptors

Ascites Diagnostic Errors Endometriosis Ovarian Neoplasms Ovarian Neoplasms Pleural Effusion Ascites Ascites Diagnosis, Differential Diagnostic Errors Endometriosis Endometriosis Female Humans Middle Aged Ovarian Neoplasms Ovarian Neoplasms Palpation Pleural Effusion Pleural Effusion

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Cited by (34)

Source provenance

europepmc
last seen: 2026-08-02T06:10:09.037253+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:15:18.313808+00:00
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