Endometriosis mimicking advanced ovarian cancer
Case report
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⤵ 33 in-corpus citations
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This case report details a patient presenting with endometriosis that mimicked advanced ovarian cancer, highlighting the importance of considering benign conditions in the differential diagnosis of suspected malignancies.
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Abstract
OBJECTIVE: To report a case of endometriosis associated with massive ascites, pleural effusion, and extremely elevated Ca-125.
DESIGN: Case report.
SETTING: University hospital.
PATIENT(S): A 46-year-old, white nulligravida with bilateral adnexal masses, Ca-125 of 3,504 U/mL, abdominal pain, ascites, and a pleural effusion.
INTERVENTION(S): Chemotherapy followed by exploratory laparotomy for suspected ovarian cancer.
MAIN OUTCOME MEASURE(S): Surgical findings and histopathology.
RESULT(S): Intraoperative examination and histology ruled out malignancy but found stage IV endometriosis.
CONCLUSION(S): In rare instances advanced endometriosis may be associated with ascites, pleural effusions, and large pelvic masses. For this reason endometriosis should be included in the differential diagnosis of reproductive-age women presenting with apparent ovarian malignancy.
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References (8)
- Ascites due to endometriosis via openalex
- Endometriosis and ascites via openalex
- Extrapelvic endometriosis via openalex
- Large bloody ascites in association with pelvic endometriosis: case report and literature review via openalex
- Massive ascites and pleural effusions associated with endometriosis via openalex
- Massive ascites associated with endometriosis via openalex
- W2100281208 via openalex
- W1980685727 via openalex
Cited by (34)
- Endometrioma With Hemorrhagic Ascites Mimicking Ovarian Malignancy: A Case Report 2026
- Endometriosis-associated massive ascites in a young Nigerian lady 2023
- Pleural effusion secondary to endometriosis: A systematic review 2023
- Peritoneal endometriosis presenting as fever of unknown origin, ascites and peritoneal miliary spread: A rare case report and review of the literature 2022
- Clinicopathological Characteristics and Outcomes of Patients With Endometriosis-Related Hemorrhagic Ascites: An Updated Systematic Review of the Literature 2022
- Endometriosis-Associated Ovarian Cancer: What Are the Implications for Women with Intact Endometrioma Planning for a Future Pregnancy? A Reproductive Clinical Outlook 2022
- Endometriosis-Related Pleural Effusion: A Case Report and a PRISMA-Compliant Systematic Review 2021
- Clinical Presentation and Management of Endometriosis-Related Hemorrhagic Ascites: A Case Report and Systematic Review of the Literature 2021
- Gross Ascites Secondary to Endometriosis: A Rare Presentation in Pre-Menopausal Women 2021
- Gynecology & Obstetrics Case report 2020
- Novel triple therapy for hemorrhagic ascites caused by endometriosis: A case report 2020
- Clinical implication of endometriosis in the surgical management of early ovarian cancer 2020
- Endometriosis-Associated Massive Ascites in an Asian Woman: A Case Report of a Rare Clinical Entity 2020
- Novel triple therapy for hemorrhagic ascites caused by endometriosis: A case report 2020
- Endometriosis on the surface of the uterus mimicking a malignant tumor: A case report with literature review 2019
- Endometriosis Mimicking an Advanced Malignant Tumor 2016
- Recurrent massive ascites due to mossy endometriosis 2016
- Histology of endometriosis-associated ovarian carcinomas 2015
- A pseudoneoplastic finding of deep endometriosis: laparoscopic triple segmental bowel resection 2014
- Endometriosis after surgical menopause mimicking pelvic malignancy: surgeons' predicament 2014
- A Case Presentation: Decidualized Endometrioma Mimicking Ovarian Cancer during Pregnancy 2013
- Endometriosis Presenting with Massive Ascites and Pleural Effusion: A Case Report 2013
- Severe endometriosis may be considered in the differential diagnosis in young women presenting massive hemorrhagic ascites 2011
- Relation of high CA125 and CA19-9 levels with recent rupture of endometrioma 2011
- Clear cell adenocarcinoma of the ovary arising in atypical endometriosis: a report of eight cases 2011
- Endometriosis-associated infertility: surgery and IVF, a comprehensive therapeutic approach 2010
- A systematic review: endometriosis presenting with ascites 2010
- Endometriosis mimicking ovarian cancer in the setting of acquired immune deficiency syndrome 2009
- Ascites and Ileus due to Endometriosis 2009
- Pathophysiology of cyclic hemorrhagic ascites and endometriosis 2008
- Massive ascites as a presentation in a young woman with endometriosis: a case report 2008
- Differential diagnosis of gynecologic organ-related diseases in women presenting with ascites 2008
- Recurrent hemorrhagic ascites: a rare presentation of endometriosis 2007
- 10.51847/6hd0rsbqk9g828 2000
Source provenance
- europepmc
- last seen: 2026-10-19T06:17:24.038039+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:03:51.313027+00:00
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