Case Hepatic Endometriosis: A Continuing Diagnostic Dilemma

article OA: gold CC0 ⤵ 29 in-corpus citations
AI-generated summary by claude@2026-06, 2026-06-07

This case describes a postmenopausal woman with a liver mass that mimicked a tumor or cystadenoma but was ultimately diagnosed as hepatic endometriosis via histology after surgical enucleation.

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Abstract

BACKGROUND: Intraparenchymal endometriosis of liver is rare. It may present as liver tumour and the diagnosis is not usually established till after surgery. CASE OUTLINE: A 48-year-old postmenopausal woman presented with right upper quadrant pain and a cystic liver mass. Liver function tests and tumour markers (alphaFP, CEA, CA 19-9, and CA 125) were normal. Radiological imaging (USS, CT and MRI) suggested a thick walled cystic mass involving segments IV and VIII with complex intracystic septations. Frozen section at operation suggested a benign cystadenoma. The cyst was enucleated using a CUSA (Cavitron ultrasonic aspirator). The final histology confirmed endometriosis. DISCUSSION: Eleven cases of hepatic endometrioma have been reported and only four in postmenopausal women. Preoperative diagnosis poses a challenge and so far none of the cases have been diagnosed preoperatively. Surgery remains the treatment of choice. Accurate diagnosis at time of operation may avoid extensive liver surgery and its associated morbidity.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Liver Diseases Endometriosis Endometriosis Female Humans Liver Liver Liver Diseases Liver Diseases Middle Aged

Citation neighborhood

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References (17)

Cited by (29)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:14:05.573375+00:00
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